miR-3940-5p level was lower in non-small cell lung cancer (NSCLC) tumor tissues than that in the matched tumor-adjacent tissues and correlated with clinicopathological features. Cyclin D1 (CCND1), a key driver of malignant transformation in NSCLC, was overexpressed in many cancers, including NSCLC. The ubiquitin specific peptidase-28 (USP28) was also overexpressed in NSCLC and associated with p...

The present study investigated the expression of miR-150 and miR-3940-5p in non-small cell lung carcinoma (NSCLC) and its relationship with clinicopathologic features. Samples included tumor, tumor-adjacent and normal lung parenchyma tissues from 90 NSCLC patients and 17 cases of embryonic lung cDNA. The expression levels of miR-150, miR-18b-5p, m...

We investigated the effects of growth hormone-releasing hormone (GHRH) antagonists, JV-1-65 and JV-1-63, and bombesin/gastrin-releasing peptide (BN/GRP) antagonist RC-3940-II on DMS-153 human small cell lung carcinoma xenografted into nude mice. Treatment with 10 microg/day JV-1-65 or RC-3940-II decreased tumor volume by 28% (P < 0.05) and 77% (P < 0.01), respectively, after 42 days compared wi...

I will give a concise overview of mesons with heavy quarks including p-wave charmed mesons and charmonium (or charmonium-like) states such as X(3872), Y(4260), X(3940), Y(3940), Z(3930) etc. The effect from the nearby S-wave open channels on the quark model spectrum is emphasized.

The linearity and parallelism of Regge trajectories is combined with a hyperfine splitting relation in multiplet to study charmonium spectrum. It is found that predictions to the spectrum of 1D multiplet could be made once another 1D state is confirmed. The newly observed X(3872), Y (3940), X(3940), Y (4260) and Z(3930) are studied within the charmonium framework. PACS numbers: 11.55.Jy, 12.39....

In this paper, we study the $X(3860)$ production associated with $J/\psi$ via $e^{+}e^{-}$ annihilation at next-to-leading-order (NLO) QCD accuracy, within nonrelativistic (NRQCD) framework. Under hypothesis of $J^{PC}_{X(3860)}=0^{++}$, predicted total cross sections agree well Belle's measurements $\sqrt{s}=\Upsilon(4S,5S)$, while theoretical results given by $2^{++}$ significantly undershoot...

Animal models play a key role in the development of novel treatments for human disease. This is particularly true for rare diseases – defined as disorders that affect less than 1 in 2000 people in the human population – for which, very often, there are no effective methods of treatment. Pharmaceutical companies are increasingly focussing on the development of therapies for the more than 7000 ra...

The primary goal of this paper is to shed some light on the maximality of the pointwise sum of two maximal monotone operators. The interesting purpose is to extend some recent results of Attouch, Moudafi and Riahi on the graphconvergence of maximal monotone operators to the more general setting of reflexive Banach spaces. In addition, we present some conditions which imply the uniform Brézis-Cr...