Drug resistance is becoming an obstacle in anti-cancer therapies. For target-based therapy of lung cancer, gefitinib, as the first generation of tyrosine kinase inhibitors (TKIs), demonstrated good initial response to the non-small cell lung cancer (NSCLC) patients whom harbors epidermal growth factor receptor (EGFR) mutation. However, within one year, additional EGFR mutation occurred, leading...

Abstract Introduction It has been documented that newborn’s sleep is strongly associated with maternal and paternal sleep. However, mothers seem to be more affected by their infant’s than fathers. These associations are not well known in families of premature newborns yet. This was the objective present study. Methods 30 (mothers, fathers infants) participated this study one month after dischar...