The histone demethylase JMJ14 catalyzes histone demethylation at lysine 4 of histone 3 and is involved in transcriptional repression and flowering time control in Arabidopsis. Here, we report that JMJ14 is physically associated with two previously uncharacterized NAC transcription factors, NAC050 and NAC052. The NAC050/052-RNAi plants and the CRISPR-CAS9-mediated nac050/052 double mutant plants...

BACKGROUND/AIMS There is a need for new anti-asthmatic medications with fewer side effects. NDC-052, an extract of the medicinal herb Magnoliae flos, which has a long history of clinical use, was recently found to have anti-inflammatory effects. Herein, we evaluated the effects of NDC-052 as an add-on therapy in patients with mild to moderate asthma using inhaled corticosteroids (ICS). METHOD...

The metal deficient (Z = Z⊙/41) Blue Compact Dwarf Galaxy (BCD) SBS0335-052 was observed with ISOCAM between 5 and 17μm. With a L12μm/LB ratio of 2.15, the galaxy is unexpectedly bright in the mid-infrared for such a low-metallicity object. The mid-infrared spectrum shows no sign of the Unidentified Infrared Bands, which we interpret as an effect of the destruction of their carriers by the very...

Introduction and background Aflatoxins are a hazard in foods because they are potent carcinogens, capable of causing cancer in nearly all animal species studied. Aflatoxins are also acute, chronic and genotoxic poisons (1). In addition, recent evidence suggests strongly that aflatoxins can be immunosuppressive (2). The primary sources of aflatoxins are the common fungi Aspergillus flavus and th...

We recently reported that formation of allopolyploid wheat was accompanied by rapid nonrandom changes in low-copy noncoding DNA sequences. In this report we show that following allopolyploidization, changes also occurred in coding sequences. Genomic DNA of nine different newly synthesized amphiploids of different ploidy levels and their parental lines was digested with five restriction enzymes ...

1 Laboratory of Immunobiology, Department of Marine Life Sciences, Jeju National University, Jeju 690-756, Korea; E-Mail: [email protected] 2 Department of Urology, Chungbuk National University College of Medicine, Cheongju 361-763, Korea; E-Mail: [email protected] 3 Department of Biochemistry, College of Oriental Medicine, Dongeui University, Busan 614-052, Korea 4 Department of Biomater...

The striking similarity between the solar distribution of r-element abundances in the 56 ≤ Z ≤ 76 range and the corresponding abundance pattern observed in the ultra-metalpoor star CS 22892-052 is analysed. It is found that such an observation does not necessarily imply that the whole A >∼ 70 distribution of r-nuclides, including Th, suspected to have been engulfed in CS 22892-052 at the same t...

First results are reported of a new abundance study of neutron-capture elements in the ultra-metal-poor (&sqbl0;Fe&solm0;H&sqbr0;=-3.1) halo field giant star CS 22892-052. Using new high-resolution, high signal-to-noise ratio spectra, abundances of more than 30 neutron-capture elements (Z>30) have been determined. Six elements in the 40<Z<56 domain (Nb, Ru, Rh, Pd, Ag, and Cd) have been detecte...