Sandeep C Chaudhary, Tripti Singh, Sarang S Talwelkar, Ritesh K Srivastava, Aadithya Arumugam, Zhiping Weng, Craig A. Elmets, Farrukh Afaq, Levy Kopelovich and Mohammad Athar* Department of Dermatology, University of Alabama at Birmingham, 1530 3rd Avenue South, VH 509, Birmingham, AL 35294-0019, Division of Cancer Prevention, National Cancer Institute, 6130 Executive Blvd, Suite 2114, Bethesda...

We analyze the structuture of a large metabolic network, that of the energy and biosynthesis metabolism of Escherichia coli. This network is a paradigmatic case for the large genetic and metabolic networks that functional genomics efforts are beginning to elucidate. To analyze the structure of networks involving hundreds or thousands of components by simple visual inspection is impossible, and ...

BACKGROUND Endometriosis is a common gynaecological problem of uncertain aetiology. It affects primarily young, reproductive-aged women and can result in chronic pelvic pain and infertility. Current approved therapies have significant side-effects and hysterectomy is employed as a final solution. ERB-041 is a selective estrogen receptor-beta (ERbeta) agonist that has anti-inflammatory activity ...

We introduce an e cient algorithm to compute the homomorphism induced in (relative) homology by a continous map. The algorithm is based ∗Research supported in part by NSF Grant 0107396 †Partially supported by the Polish Committee for Scienti c Research (KBN), grant no. 2 P03A 041 24. ‡Partially supported by the Polish Committee for Scienti c Research (KBN), grant no. 2 P03A 041 24. Permanent ad...

The excitatory roles of EP3 receptors at the peripheral afferent nerve innervating the rat urinary bladder have been evaluated by using the selective EP3 antagonist (2E)-3-[1-[(2,4-dichlorophenyl)methyl]-5-fluoro-3-methyl-1H-indol-7-yl]-N-[(4,5-dichloro-2-thienyl)sulfonyl]-2-propenamide (DG-041). The bladder rhythmic contraction model and a bladder pain model measuring the visceromotor reflex (...

Accumulating evidence suggests that ubiquitin E3 ligases are involved in cancer development as their mutations correlate with genomic instability and genetic susceptibility to cancer. Despite significant findings of cancer-driving mutations in the BRCA1 gene, estrogen receptor (ER)-positive breast cancers progress upon treatment with DNA damaging-cytotoxic therapies. In order to understand the ...

Recenzja książki: Piotr Jaworski, Księga Jonasza . Wstęp, przekład, miejsca paralelne, komentarz i ekskursy (Biblia Lubelska; Lublin: Wydawnictwo KUL 2022). Ss. 77. ISBN: 978-83-8288-041-0

We present a new experimental value for the magnetic moment of the electron bound in hydrogenlike carbon (12C5+): g(exp) = 2.001 041 596 (5). This is the most precise determination of an atomic g(J) factor so far. The experiment was carried out on a single 12C5+ ion stored in a Penning trap. The high accuracy was made possible by spatially separating the induction of spin flips and the analysis...