نتایج جستجو برای: 0.19)
تعداد نتایج: 1968 فیلتر نتایج به سال:
Brucella species are the most important zoonotic pathogens worldwide and cause considerable harm to humans and animals. In this study, we presented the complete genome of B. suis 019 isolated from sheep (ovine) with epididymitis. B. suis 019 has a rough phenotype and can infect sheep, rhesus monkeys and possibly humans. The comparative genome analysis demonstrated that B. suis 019 is closest to...
Polymyxin B and colistin are exclusively active against Gram-negative pathogens and have been used in the clinic as a last-line therapy. In this study, we investigated the antimicrobial activity of a novel polymyxin, FADDI-019, against Staphylococcus aureus. MIC and time-kill assays were employed to measure the activity of FADDI-019 against S. aureus ATCC 700699. Cell morphology was examined wi...
So what is the Tadpole Topaz and what does it have to offer? That would be a tough, rugged notebook computer with a large 15.1-inch 1400 x 1050 pixel sunlight-viewable display and enough performance to power through very demanding applications, delivering stunning graphics performance in the process. While the Topaz is compact and lightweight by military standards, that still means a 12-pound p...
The impact of increasing the number of crosses per parent (k) on the efficiency of roguing seed orchards (backwards selection, i.e., reselection of parents) was examined by using Monte Carlo simulation. Efficiencies were examined in light of advanced-generation Douglas-fir (Pseudotsuga menziesii (Mirb.) Franco) tree improvement programs where information is available from previous generations, ...
Don’t you just hate it when some marketing guy labels something as “ultimate”? Well, I’ve found something that really should be labeled as “ultimate”. It’s General Dynamics (GD) Itronix’ brand-new DynaVue outdoor-readable touch-screen display technology. The American Heritage Dictionary defines “ultimate” as “representing or exhibiting the greatest possible development or sophistication”, and t...
Introduction Fosaprepitant, an intravenous (IV) aprepitant prodrug for chemotherapy-induced nausea and vomiting prophylaxis, is associated with systemic and infusion-site reactions attributed in part to its surfactant, polysorbate 80. HTX-019 is an IV aprepitant formulation free of polysorbate 80 and other synthetic surfactants. Materials and methods This open-label, single-dose, randomized, ...
Apelin peptide analogues displaying bias towards G protein signalling pathways have beneficial cardiovascular actions compared with the native peptide in humans in vivo. Our aim was to determine whether small molecule agonists could retain G protein bias. We have identified a biased small molecule, CMF-019, and characterised it in vitro and in vivo. In competition radioligand binding experiment...
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