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A. Sivalingam, N. M. Hariharan, T. Kannadasan, M. Thirumarimurugan, and S. Gopalakrishnan Department of Chemical Engineering, Coimbatore Institute of Technology, Coimbatore – 641 014, Department of Chemical Engineering, Coimbatore Institute of Technology, Coimbatore – 641 014 Chemical Engineering, Coimbatore Institute of Technology, Coimbatore – 641 014 and Anna University of Technology, Coimba...
BACKGROUND AVI-014 is an egg white-derived, recombinant, human granulocyte colony-stimulating factor (G-CSF). This healthy volunteer study is the first human investigation of AVI-014. METHODS 24 male and female subjects received a single subcutaneous injection of AVI-014 at 4 or 8 mcg/kg. 16 control subjects received 4 or 8 mcg/kg of filgrastim (Neupogen, Amgen) in a partially blinded, parall...
PURPOSE First-in-human phase I trial to determine the safety, pharmacokinetics, and antitumor activity of BIND-014, a novel, tumor prostate-specific membrane antigen (PSMA)-targeted nanoparticle, containing docetaxel. EXPERIMENTAL DESIGN Patients with advanced solid tumors received BIND-014 every three weeks (n = 28) or weekly (n = 27), with dose levels ranging from 3.5 to 75 mg/m(2) and 15 t...
The mating strategies of male and female Ectropis oblique Prout were investigated with the aid of male antennae as an electroantennogram (EAG) detector and capillary-GC analysis. Each male was capable of mating with several females, but females that had received a spermatophore mated only once. Antennae dissected from males 0, 1, 2, 3, and 4 d post-mating and antennae from virgin males of corre...
Any symmetric mixed-strategy equilibrium in a Tullock contest with intermediate values of the decisiveness parameter (“ 2)hascountablyinfinitelymanymasspoints.Allprobabilityweightisconcentratedonthosemasspoints, whichhavethezerobidastheirsolepointofaccumulation.Withcontestantsrandomizingoveranon− convexset, thereisacostofbeinghalfhearted, whichisabsentfromboththelotterycontestandtheall−payaucti...
Introduction Whether atherosclerosis is increased or not in Familial Mediterranean Fever (FMF) is a much debated issue. Carotid artery intima media thickness (IMT) a surrogate marker for subclinical atherosclerosis is found to be increased in a number of studies [1-5], however this contrasts with the lack of increased frequency of atherosclerotic plaques[1-5]. Also, population surveys do not in...
We consider the construction of inverted hybrid inflation models in which the vacuum energy during inflation is at the TeV scale, and the inflaton couples to the Higgs field. Such models are of interest in the context of some recently proposed models of electroweak baryogenesis. We demonstrate how constraints on these models arise from quantum corrections, and how selfconsistent examples may be...
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