The cellular basis of immunological memory remains a controversial issue. Here we show that basophils bound large amounts of intact antigens on their surface and were the main source of interleukins 6 and 4 in the spleen and bone marrow after restimulation with a soluble antigen. Depletion of basophils resulted in a much lower humoral memory response and greater susceptibility of immunized mice...

Second heart field (SHF) progenitors exhibit continued proliferation and delayed differentiation, which are modulated by FGF4/8/10, BMP and canonical Wnt/β-catenin signaling. PTEN-Akt signaling regulates the stem cell/progenitor cell homeostasis in several systems, such as hematopoietic stem cells, intestinal stem cells and neural progenitor cells. To address whether PTEN-Akt signaling is invol...

The recoveryphaseafterkidney ischemia/reperfusion(IR) injury isoften associated with the suppression of inflammation and the proliferation of tubular epithelial cells (TECs). The duration of this phase is often determined by the suppression of inflammation and the proliferation of TECs. Several lines of evidence suggest that IκB kinase α (IKKα) not only promotes the production of anti-inflammat...

Saehwa Kim School of EE and CS Seoul National University Seoul 151-742, Korea [email protected] Michael Buettner School of EE and CS Seoul National University Seoul 151-742, Korea [email protected] Mark Hermeling IBM Software Group IBM Singapore Pte Ltd Singapore 486072, Singapore. [email protected] Seongsoo Hong School of EE and CS Seoul National University Seoul 151-742, Ko...

This book is a Festschrift that grew out of a workshop celebrating the 65th birthday of Grzegorz Rozenberg. Among many other accomplishments, Rozenberg coined the phrase “Natural Computing,” co-founded the journal of the same name, and also co-founded Theoretical Computer Science C (Theory of Natural Computing), and the Springer book series Natural Computing, of which this volume is a part. The...

Inflammation and genetics have key roles in the pathogenesis of atherosclerosis, and the etiology of myocardial infarction (MI). Recent studies have indicated that lower serum levels of fetuin-A may accelerate the vascular mineralization process, which leads to pathophysiological conditions, such as coronary heart disease and chronic renal failure. The aim of the present study was to evaluate t...

1Korea Bridge Design and Engineering Research Center, Seoul National University, Seoul 151-742, Korea 2Structure Department, DONG IL Engineering Consultants Co. Ltd., Seoul 138-200, Korea 3Department of Civil Engineering, Seoul National University, Korea 4Structural Design Department, Korea Engineering Consultants Corp., Seoul 143-715, Korea 5School of Civil, Urban, and Geosystem Engineering, S...

a Institute of Computer Science, Atomic Energy Research Establishment, Bangladesh Atomic Energy Commission, Savar, Dhaka, Bangladesh b Program in Regional Information, College of Agriculture and Life Sciences, Seoul National University, San 56-1, Sillim-dong, Seoul 151-742, Republic of Korea c Research Institute for Agriculture & Life Sciences, Seoul National University, Gwanak-599, Gwanak-ro, ...