Es necesario el desarrollo de software educativo que permita la implementación prácticas laboratorio. En este trabajo se presenta diseño y del programa Lab-NMDAR, constituido por tres simuladores para enseñanza-aprendizaje electrofisiología receptor NMDA: (1) simulador NMDAR-Bloqueo Mg2+, (2) NMDAR-Glicina (3) canal único NMDA-Bloqueo Mg2+. El implementó en Visual Basic® ambiente Windows®. Con ...

Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis is an autoimmune inflammation of the brain parenchyma mediated with autoantibodies against NMDA receptors in neuronal cells. It most common form encephalitides pediatric patients. In this case report, we present a child anti-NMDAR encephalitis, refractory to first-line therapy.

Traumatic brain injury is a significant cause of mortality in young adults and disability all age groups. This followed by secondary involving various processes, such as oxidative stress which induce neuronal apoptosis. The present study aimed to analyze the active compounds Citrus sinensis predict its antioxidative activity traumatic injury. Liquid chromatography/high resolution mass ...

It has been reported that ketamine as an uncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist has also non-NMDA receptor antagonist properties. We recently found that ketamine (20 ?M) affected differently induction of NMDA receptor-mediated long-term potentiation (LTP) when administered 30 min prior to tetanic Primed-Bursts (PBs) stimulation. On the other hand, ketamine also influenced...

background: considering that cannabinoids protect neurons against neurodegeneration, in this study, the neuroprotective effect of win55,212-2 in paraoxon induced neurotoxicity in pc12 cells and the role of the n-methyl-d-aspartate (nmda) receptor were evaluated. materials and methods: in this study pc12 cells were maintained in dulbecco's modified eagle’s medium (dmem+f12) culture medium supple...

It has been reported that ketamine as an uncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist has also non-NMDA receptor antagonist properties. We recently found that ketamine (20 ?M) affected differently induction of NMDA receptor-mediated long-term potentiation (LTP) when administered 30 min prior to tetanic Primed-Bursts (PBs) stimulation. On the other hand, ketamine also influenced...