We report the sequence of the frpS gene of the cyanobaderium Synechocysfis sp. PCC 6803. This gene was cloned from a plasmid library by functional complementation of a frpS mutant of Escherichia coli K-12. Among the known frpS sequences, the Synechocysfis gene bears the greatest homology to the duplicated frpS genes of Arabidopsis thaliana and Zea mays. Southern and northern blotting analyses s...

The physiological basis of serial T-wave abnormalities associated with myocardial infarction was studied. After coronary artery ligation in dogs, ventricular functional refractory periods (FRPs) were measured at five to eight epicardial, intramural, and endocardial sites. FRPs measured during acute ischemia shortened an average of 26 msec. FRPs measured 24 to 72 hr after coronary ligation were ...

Feedback monitoring and adaptation of performance involve a medial reward system including medial frontal cortical areas, the medial striatum, and the dopaminergic system. A considerable amount of data has been obtained on frontal surface feedback-related potentials (FRPs) in humans and on the correlate of outcome monitoring with single unit activity in monkeys. However, work is needed to bridg...

Since the late 1980s, the civil engineering community has become interested in the application of Fiber Reinforced Polymers (FRP) to the construction industry. These materials are comprised of very strong fibers and a resin matrix. The most popular application of FRPs has been in repair and rehabilitation of structures. In this technique, FRPs are bonded to the exterior surface of the structura...

The fiber reinforced plastics (FRPs) are being used widely in the most diverse applications ranging from the aerospace to the sports goods industry. Drilling in particular is important to facilitate the assembly operations of structurally intricate composite products. The drilling of holes in FRPs leads to drilling induced damage which is an important research area. The researchers worldwide ha...

A matrix-assisted laser desorption/ionization (MALDI) mass spectrometric (MS) survey of the major peptides in the stellar, fin and pallial nerves and the posterior chromatophore lobe of the cephalopods Sepia officinalis, Loligo opalescens and Dosidicus gigas has been performed. Although a large number of putative peptides are distinct among the three species, several molecular masses are conser...

The US Food and Drug Administration (FDA) has four facilitated regulatory pathways (FRPs): Fast Track (FT), Breakthrough Therapy (BTD), Priority Review (PR), and Accelerated Approval (AA). Only PR specifies an expedited review timeline (6 months). We sought to determine to what extent the combination of two or more FRPs influenced development and approval times. We developed a "metro map" to il...