Momordica charantia L. is a herbaceous climbing plant in the genus Momordica of family Cucurbitaceae. It is to study the chemical constituents of Momordica charantia L. leaves and establish the method for determination of their total saponin content. Momordica charantia L. leaves are isolated and purified by silica gel and Sephadex LH-20 column chromatographies, and the resulting compounds are ...

1. Duke AJ. Handbook of Medicinal Herbs, Second edition. Boca Raton: CRC Press Inc; 1989: p. 315-6. 2. Cunnick J, Takemoto D. Bitter melon (Mormordica charantia). J Nat Med 1993;4:16-21. 3. Chandrasekar B, Mukherjee B, Mukherjee SK. Blood sugar lowering potentiality of selected Cucurbitaceae plants of Indian origin. Indian J Med Res 1989;90:300–5. 4. Srivastava Y, Venkatakrishna-Bhatt H, Verma ...

Sulfated derivatives of polysaccharide from Momordica charantia L. (MCPS) with different degree of sulfation (DS) were synthesized by chlorosulfonic acid method with ionic liquids as solvent. Fourier transform infrared spectra and 13C nuclear magnetic resonance spectra indicated that C-6 substitution was predominant in MCPS compared with the C-2 position. Compared with the native polysaccharide...

Background: Momordica charantia is used in China for its jianghuo (heat-clearing and detoxifying) effects. The concept of shanghuo (the antonym of jianghuo, excessive internal heat) in traditional Chinese medicine is considered a type of stress response of the body. The stress process involves internal organs, especially the liver. Objective: We hypothesized that Momordica charantia water extra...

Focusing on a functional component of Momordica charantia, saponin, we investigated its effects on serum glucose and neutral fat levels. Saponin was extracted as a butanol-soluble fraction (saponin fraction) from hot blast-dried Momordica charantia powder. The disaccharidase-inhibitory activity and the pancreatic lipase-inhibitory activity of the saponin fraction were measured, and in vivo suga...

The quality of vegetable extracts is influenced by parameters such as: extraction method, extracting liquid, vegetable matter granulometry and plant:solvent ratio. The standardization of these parameters in obtaining extracts is of great importance in order to guarantee their quality. The spectrophotometric trial based on the formation of complexes with aluminum chloride was applied to evaluate...

Microbial shelf life quality assessment of a sensory evaluated ready-to-serve Momordica charantia L. (Bitter Gourd) drinkP E Chern, N A Mahyudin, H Ghazali, K Mahmud Ab Rashid

In an attempt to screen the hypogly-caemic activity of Momordica charantia fruit (Karela) the proximate analysis, alkaloidal tests and its effects on blood glucose levels of normal male albino rabbits were determined. Whole dried and powdered Momordica charantia fruit was used for this purpose and blood glucose was determined by O-toluidine method at various time intervals. The proximate analys...