Background: Until recently, a gene polymorphism in the promoter region of endothelial nitric oxide synthase has been suggested as a risk factor for thromboangiitis obliterans (TAO) development. The aim of this study was to compare the metabolites of nitric oxide (NO) and its backup, heme-oxygenase-1 (HMOX1), between TAO patients and those of a smoking control group matched by race, age, sex, an...

Translating fine-grained activity detection (e.g., phone ring, talking interspersed with silence and walking) into semantically meaningful richer contextual information on a call for 20 minutes while exercising) is essential towards enabling range of healthcare human-computer interaction applications. Prior work has proposed building ontologies or temporal analysis patterns limited success in c...

This paper attempts to present the Taoist understanding of evil. In the Taoist tradition, especially in Tao Te Ching, evil is divided into two categories: causal evil and consequential evil. Causal evils are those evils that are said to be the causes of other evils; consequential evils are those that are said to be the consequences of the causal evils. Causal evils originate from human will, an...

Graphical Abstract „My next goal is to conduct peptide assembly on biointerfaces for bioanalysis … The most important thing I have learned from my students think outside of the box.“ Find out more about Tao Jiang in his Introducing Profile.

Trypanosome alternative oxidase (TAO) is the cytochrome-independent terminal oxidase of the mitochondrial electron transport chain. TAO is a diiron protein that transfers electrons from ubiquinol to oxygen, reducing the oxygen to water. The mammalian bloodstream forms of Trypanosoma brucei depend solely on TAO for respiration. The inhibition of TAO by salicylhydroxamic acid (SHAM) or ascofurano...

Thromboangiitis obliterans (TAO) is a thrombotic-occlusive as well as an inflammatory peripheral vascular disease with unknown etiology. Recent evidence has supported the immunopathogenesis of the disease, however, the factors contributing to the altered immune function and vascular tissue inflammation are still unclear. This review was intended to collate the more current knowledge on the regu...