background & importance: disc herniation is defined as the prolapsed of material disc into the spinal canal. if the disc fragment is free in spinal canal, it is called sequestration disc fragment. occasionally, alteration in sequestration disc fragment makes the diagnosis of the disc herniation, challenging. case presentation: we reviewed a rare case of the cervical sequestrated disc herniation...

even though intervertebral disc degeneration can be found in the natural course of alkaptonuria, detection of the disease by black disc color change in a patient without any other presentation of alkaptonuria is an exceptionally rare condition. we have reported a very rare case of alkaptonuria presented with low back pain and steppage gait in a 51-year-old male with a complaint of chronic low-b...

abstract   background: far lateral discal herniation is an uncommon disorder and is difficult to assess by physical examination alone. this study is designed to define clinical and epidemiological findings and to establish the indications of surgical and medical treatment for flldh.   methods: between 2000 and 2005, a total of 2035 patients with lumbar disc herniation underwent surgical discect...

conclusions in this study, we found that in spite of previous beliefs, discopathies were not common etiologies of lbp. thus, even in patients with proven ldh by imaging studies, the physician should perform a thorough evaluation for other causes of lbp to avoid unnecessary lumbar surgeries. results in our study, among 1250 patients with proven ldh by mri, 500 patients (40%) had chronic lbp and ...

in view of potential biological activities of small molecule polyamides, we synthesized some novel n-(2-aminoethyl)-1-benzyl-2- (alkylthio)-1h-imidazole-5-carboxamide (7a,b), and n-(2-(1-benzyl-2-(alkylthio) -1h-imidazole- 5-carboxamido) ethyl)-1-benzyl-2- (alkylthio)-1h-imidazole-5-carboxamides (8a,b) as antitumor agents. the antitumor activity of compounds 7a,b and 8a,b was studied at concent...

purpose: to report a case who had optic disc duplication, a rare congenital disorder characterized by two well-defined discs in one eye. case report: a 19 months-old child presented with unilateral epiphora in the right eye since birthday. the right eye was smaller than the left eye and mild ptosis was apparent. nasolacrimal duct probing was performed under general anesthesia. the examination r...

a woman presenting with severe right lower quadrant (rlq) abdominal pain is presented here. she was evaluated for all usual cause of such pain. laboratory tests and abdominal and pelvic sonography was normal. mri revealed l1-l2 disc herniation.