نتایج جستجو برای: نشانگر CA15-3

تعداد نتایج: 1819290  

Journal: :Anticancer research 2013
Benjamin Nisman Ofra Maimon Tanir Allweis Luna Kadouri Bella Maly Tamar Hamburger Tamar Peretz

AIM To investigate the prognostic significance of cancer antigen 15-3 (CA15-3) in primary breast cancer (BC). PATIENTS AND METHODS This prospective study included 368 women: 62 patients with benign breast disease (BBD), 159 patients with invasive BC and 88 healthy blood donors (control). The median follow-up was 76 months (range, 43-99 months). Serum CA15-3 was measured with LIAISON® CA15-3® ...

Journal: :Environmental Health Perspectives 1995
Kellyn Betts

The usefulness of post-operatively serial serum CA15-3 determination with CEA and TPA was evaluated in a group of 285 breast cancer patients. In particular, the CAI 5-3 sensitivity to 'early' diagnosis and monitoring of the response to treatment of breast cancer relapses, was compared with those of the two other markers in order to'define the most suitable association. Moreover, in a group of 1...

ژورنال: :مجله دانشگاه علوم پزشکی مازندران 0
فرشاد نقش وار f naghshvar faculty of medicine -mazandaran university of medical science, sari, iranمتخصص پاتولوژی، عضو هیأت علمی (استادیار) دانشگاه علوم پزشکی مازندران ژیلا ترابی زاده zh torabizadeh امید عمادیان o emadian مهران قهرمانی m gahremani

سابقه و هدف: سرطان پستان شایع ترین سرطان در جنس مونث می باشد. 7 تا 11 درصد زنان در طول عمر خود و سالیانه یک میلیون نفر در کل دنیا به آن مبتلا می شوند. علی رغم پیشرفت هایی که در روش های تشخیص موارد متاستاتیک بدخیمی ها صورت گرفته است، هنوز محدودیت های فراوانی در این زمینه وجود دارد. به همین علت امروزه توجه خاصی به استفاده از روش های حساس، سریع و ارزان شده است که یکی از آن ها استفاده از نشانگرهای ...

2018
Michiko Imamura Takashi Morimoto Takashi Nomura Shintaro Michishita Arisa Nishimukai Tomoko Higuchi Yukie Fujimoto Yoshimasa Miyagawa Ayako Kira Keiko Murase Kazuhiro Araki Yuichi Takatsuka Koshi Oh Yoshikazu Masai Kouhei Akazawa Yasuo Miyoshi

BACKGROUND Although the prognosis for operable breast cancers is reportedly worse if serum carcinoembryonic antigen (CEA) and cancer antigen 15-3 (CA15-3) levels are above normal, the usefulness of this prognosis is limited due to the low sensitivity and specificity; in addition, the optimal cutoff levels remain unknown. METHODS A total of 1076 patients who were operated for breast cancers (t...

2016
San-Gang Wu Zhen-Yu He Hong-Yue Ren Li-Chao Yang Jia-Yuan Sun Feng-Yan Li Ling Guo Huan-Xin Lin

PURPOSE The clinical significance of preoperative serum levels of carcinoembryonic antigen (CEA) and cancer antigen 15-3 (CA15-3) in breast cancer is controversial. The purpose of this study was to assess the clinical value of preoperative serum levels of CEA and CA 15-3 on the risk of axillary lymph node metastasis (ALNM) in patients with breast cancer. METHODS This retrospective study analy...

2015
Yingbo Shao Xianfu Sun Yaning He Chaojun Liu Hui Liu Surinder K. Batra

BACKGROUND & AIMS The utility of measuring carcinoembryonic antigen(CEA) and cancer antigen 15-3 (CA15-3) levels in patients with breast cancer remains controversial. The present study aims to investigate the prognostic value of preoperative serum CEA and CA15-3 levels in breast cancer patients. METHODS Serum preoperative CEA and CA 15-3 concentration levels were measured in a total of 432 br...

Journal: :The European respiratory journal 1988
K Shimokata Y Totani K Nakanishi M Yamamoto Y Hasegawa H Kawatsu H Sasou T Murate S Ichiyama T Kurasawa

Pleural fluid levels of the cancer antigen 15-3 (CA15-3) detected by monoclonal antibodies (115D8 and DF3) were determined in 40 patients with carcinomatous pleural effusions and in 41 patients with tuberculous pleural effusions. Using a cut off level of 16 U/ml, 15 of the 40 carcinomatous fluids but none of the 41 tuberculous fluids were positive. Pleural fluid levels of CA15-3 were not correl...

2017
Shuang Fu Zhi-Yuan Yun Ming-Ming Cui Hongxue Meng Cheng Qian Tiemin Liu Zhi-Ping Liu Rui-Tao Wang Kai-Jiang Yu

Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer death among females. However, mammographic diagnosis is sometimes non-conclusive with a Breast imaging Reporting and Data System (Bi-RaDS) result of 0. Cancer antigen 15-3 (CA15-3) is the most widely used serum tumor marker for breast cancer screening. Platelet distribution width (PDW) is an early indicator of...

Journal: :Annals of oncology : official journal of the European Society for Medical Oncology 2007
A Keshaviah S Dellapasqua N Rotmensz J Lindtner D Crivellari J Collins M Colleoni B Thürlimann C Mendiola S Aebi K N Price O Pagani E Simoncini M Castiglione Gertsch R D Gelber A S Coates A Goldhirsch

BACKGROUND We evaluated the ability of CA15-3 and alkaline phosphatase (ALP) to predict breast cancer recurrence. PATIENTS AND METHODS Data from seven International Breast Cancer Study Group trials were combined. The primary end point was relapse-free survival (RFS) (time from randomization to first breast cancer recurrence), and analyses included 3953 patients with one or more CA15-3 and ALP...

Journal: :Anticancer research 2008
Bettina Toth Rienk Nieuwland Susanne Liebhardt Nina Ditsch Kerstin Steinig Petra Stieber Andreas Rank Peter Göhring Christian J Thaler Klaus Friese Ingo Bauerfeind

BACKGROUND The aim of the present prospective case-control study was to evaluate the putative relevance of circulating microparticles (MP) as a biomarker in breast cancer patients. MATERIALS AND METHODS Endothelial cell-(EMP) and leukocyte-derived MP (LMP) were determined by flow cytometry in breast cancer patients (n = 41) and healthy controls (n = 25) and compared to carcinoembryonic antige...

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