abstract background: clinical risk index of babies (crib), score for neonatal acute physiology (snap), an update of the clinical risk index for babies score (crib ii) and score for neonatal acute physiology - perinatal extension (snap-pe) are scoring devices developed in neonatal intensive care units. this study reviewed these scoring systems in critically ill neonates to determine how well the...

the objective of this study was to determine the effects of grasp conditions (types of grasp, grasp width, glove and types of coupling) on maximal pushing force (mpf) and required pinch force (rpf) during snap fit assembly. the results indicated that the type of grasp, the type of coupling and wearing gloves have significant (p

The SNAP receptor (SNARE) complex, consisting of synaptosome-associated protein of 25 kDa (SNAP-25), synaptobrevin-2, and syntaxin-1, is involved in synaptic vesicles exocytosis. In addition, SNAP-25 has been implicated in constitutive exocytosis processes required for neurite outgrowth. However, at least three isoforms of SNAP-25 have been reported from neurons: SNAP-23, which is also present ...

Neuronal dense-core vesicles (DCVs) transport and secrete neuropeptides necessary for development, plasticity and survival, but little is known about their fusion mechanism. We show that Snap-25-null mutant (SNAP-25 KO) neurons, previously shown to degenerate after 4 days in vitro (DIV), contain fewer DCVs and have reduced DCV fusion probability in surviving neurons at DIV14. At DIV3, before de...

Soluble N-ethylmaleimide-sensitive factor attachment protein (SNAP)-25 is a neuronal SNARE protein essential for neurotransmitter release from presynaptic terminals. Three palmitoylated SNAP-25 family proteins: SNAP-25a, SNAP-25b, and SNAP-23, are expressed in the brain, but little is known about their distributions and functions. In the present study, we generated specific antibodies to distin...