background: safe exclusion and risk stratification are currently recommended for the initial management of patients with acute pulmonary embolism (ape). the aim of this study was to assess the safe exclusion and risk stratification value of d-dimer (dd) for ape when tested at the beginning of admission. materials and methods: all consecutive chinese ape patients and controls were recruited from...

Apurinic endonuclease (APE; also known as Ref-1 protein) is a key enzyme in base excision repair, cleaving apurinic sites that arise spontaneously because of the activity of DNA glycosylases. To address the question of whether APE can be modulated by genotoxic stress affecting cellular protection, we analyzed the expression of APE in Chinese hamster ovary (CHO) cells after treatment with variou...

We present a second-stage machine translation (MT) system based on a neural machine translation (NMT) approach to automatic post-editing (APE) that improves the translation quality provided by a firststage MT system. Our APE system (APESym) is an extended version of an attention based NMT model with bilingual symmetry employing bidirectional models, mt → pe and pe → mt. APE translations produce...

Objective: Acute pulmonary embolism (APE) is a highly fatal acute clinical condition. Herein, we aimed to determine the role of blood parameters in diagnosis and prognostication APE.
 Material Method: This study was conducted retrospectively on patients who had been admitted our hospital’s emergency department (ED) diagnosed with APE. Patients an RV/LV ratio greater than 0,9 Computed tomog...

OBJECTIVE The abdominoperineal excision (APE) rate, a quality of care indicator in rectal cancer surgery, has been criticised if not adjusted for confounding factors. This study evaluates variability in APE rate between centres participating in PROCARE, a Belgian improvement initiative, before and after risk adjustment. It also explores the effect of merging the Hartmann resections (HR) rate wi...

22 Objective Apurinic/apyrimidinic endonuclease-1 (APE-1) is a key enzyme 23 responsible for DNA base excision repair (BER) and is also a multifunctional protein 24 such as redox effector for several transcriptional factors. Our study was designed to 25 investigate APE-1 expression and to study its interaction with COX-2 expression and 26 VEGF production in the esophageal cancer. 27 Materials a...

Apurinic/apyrimidinic endonuclease-1 (APE-1) is a key enzyme responsible for DNA base excision repair and is also a multifunctional protein such as redox effector for several transcriptional factors. Our study was designed to investigate APE-1 expression and to study its interaction with cyclooxygenase (COX)-2 expression and VEGF production in the esophageal cancer. The expression of APE-1, COX...

The multifunctional mammalian apurinic/apyrimidinic (AP) endonuclease (APE) participates in the repair of AP sites in the cellular DNA as well as participating in the redox regulation of the transcription factor function. The function of APE is considered as the rate-limiting step in DNA base excision repair. Paradoxically, an unbalanced increase in APE protein leads to genetic instability. The...