McNulty, Harkness, Ben-Porath and Williams recently developed Personality Psychopathology Five (PSY-5) scales for the Minnesota Multiphasic Personality Inventory-A (MMPI-A). This study examined these new scales in a sample of 545 adolescents receiving inpatient psychiatric treatment. Item-level principal components analyses were employed to determine the internal structure of each PSY-5 scale a...

Besides the important role of emotional factors in the production of psychological-stress-induced analgesia (PSY-SIA), recent attention to the participation of serotonergic (5-HTnergic) neurons in the fear- and anxiety-evoking mechanism led us to examine the effects of 5-HTnergic ligands on PSY-SIA. Pretreatment of mice with 2.0 to 10 mg/kg of methysergide, a 5-HT receptor antagonist, or 1.0 to...

This study examined the utility of the MMPI-2 to predict Gray’s BIS/BAS dimensions in a sample of 193 Spanish undergraduates. Although the MMPI-2 is composed of numerous scale indices, we focused on the clinical, content, and the Personality Psychopathology-Five (PSY-5) scales. Overall, findings confirmed hypothesized associations between BIS/BAS factors and MMPI-2 indices. BIS scores demonstra...

This study investigated the utility of the MMPI-2-based Personality Psychopathology Five (PSY-5) scales (Harkness, McNulty, & Ben-Porath, 1995) in the outcome prediction of behaviorally oriented chronic-pain treatment. The PSY-5 is a dimensional descriptive system for personality and its disorders. The sample consisted of 120 consecutive chronic-back-pain patients who followed a 4-week multimod...

Phytoene synthase (PSY) catalyzes the highly regulated, frequently rate-limiting synthesis of the first biosynthetically formed carotene. While PSY constitutes a small gene family in most plant taxa, the Brassicaceae, including Arabidopsis (Arabidopsis thaliana), predominantly possess a single PSY gene. This monogenic situation is compensated by the differential expression of two alternative sp...

Journal of Lipid Research Volume 54, 2013 3303 Copyright © 2013 by the American Society for Biochemistry and Molecular Biology, Inc. Globoid cell leukodystrophy (GLD) is a rapidly progressing pediatric neurodegenerative disease caused by missing or dysfunctional lysosomal enzyme galactosylceramidase (GALC). Hallmarks of this disease include macrophage (globoid cell) infi ltration into the brain...

We explored the validity of the Psychopathology Five (PSY-5) facet scales of the adolescent version of the Minnesota Multiphasic Personality Inventory (MMPI-A; Butcher et al., 1992) in an adolescent inpatient psychiatric sample (N = 662) through a series of correlational analyses with self-report measures, therapist ratings, and chart review variables. Consistent with previous research with PSY...