A mean residence time (MRT) is an important pharmacokinetic parameter. To the author's knowledge, however, a physiologically based structure of MRT (thereafter MRT structure) has not been published so far. Primarily this is because MRT structures cannot be identified by traditional pharmacokinetic methods used for the determination of MRT. Therefore, tools from the theory of linear dynamic syst...

PURPOSE Malignant rhabdoid tumor (MRT) is a rare and highly aggressive neoplasm of young children. Current treatments have had only limited success. Epidermal growth factor receptor (EGFR) was found recently to be expressed on MRT cell lines. Gefitinib (trade name Iressa) is an oral and selective EGFR-tyrosine kinase inhibitor and has been demonstrated to be effective in inhibiting the prolifer...

Die kardiale Magnetresonanztomographie (MRT) hat sich als wichtiges nicht-invasives Diagnostikverfahren innerhalb der Kardiologie etabliert und entwickelt stetig weiter. Dieser Beitrag stellt beispielhaft drei interessante MRT-Studien letzten Monate vor, die Themen „MRT COVID-19“, „Fibrose bei Aortenklappenstenose“ künstliche Intelligenz“ behandeln. Außerdem werden neue MRT-Positionspapiere zu ...

An important component of digestive physiology involves ingesta mean retention time (MRT), which describes the time available for digestion. At least three different variables have been proposed to influence MRT in herbivorous mammals: body mass, diet type, and food intake (dry matter intake, DMI). To investigate which of these parameters influences MRT in primates, we collated data for 19 spec...

Microbeam radiation therapy (MRT), a preclinical form of radiosurgery, uses spatially fractionated micrometre-wide synchrotron-generated X-ray beams. As MRT alone is predominantly palliative for animal tumors, the effects of the combination of MRT and a newly synthesized chemotherapeutic agent JAI-51 on 9L gliosarcomas have been evaluated. Fourteen days (D14) after implantation (D0), intracereb...

It is well known that saccadic reaction times (SRT) are reduced when the target is preceded by the offset of the fixation point (FP)--the gap effect. Some authors have proposed that the FP offset also allows the saccadic system to generate a separate population of SRT, the express saccades. Nevertheless, there is no agreement as to whether the gap effect and express responses are also present f...

The MRT routing information export format represents an effective way of storing BGP routing information in binary dump files. Although a few tools exist to extract data from MRT dump files, most of them do not allow repacking or creating such MRT files. The MRT dump file manipulation toolkit (MDFMT) allows to repack parts of large MRT dump files containing BGP update messages into smaller ones...

Malignant rhabdoid tumor (MRT) is a rare and highly aggressive tumor presenting in the kidney and soft tissue in childhood. However, effective treatment for MRT has not been established. We investigated the antitumor effect of etodolac, a selective cyclooxygenase-2 inhibitor, on MRT cells in vitro using the MRT cell line FRTK-1. Etodolac induced apoptosis of FRTK-1 cells through activation of c...

BACKGROUND Manual muscle testing (MMT) is a non-invasive assessment tool used by a variety of health care providers to evaluate neuromusculoskeletal integrity, and muscular strength in particular. In one form of MMT called muscle response testing (MRT), muscles are said to be tested, not to evaluate muscular strength, but neural control. One established, but insufficiently validated, applicatio...