A regional climate model named Providing REgional Climates for Impacts Studies (PRECIS) adapted in generating rainfall scenarios for the SAARC (South Asian Association for Regional Cooperation) region. At first, PRECIS generated rainfall scenario is calibrated with ground-based observed rainfall during baseline period (1961-1990) in Bangladesh. The regression coefficients obtained through calib...

To evaluate the intervention effects of randomized controlled trials (RCT) involved in theoretical efficacy and actual clinical outcome (effectiveness). Pragmatic-Explanatory Continuum Indicator Summary (PRECIS) is a tool to help researchers make decisions in study design which is consistent with the intended purpose of their trial which can be used in the design of RCT to balance the internal ...

Results Brainstorming sessions identified the PRECIS presentation (a wheel), lack of a scoring system and domain weighting as issues for exploration in the Delphi process. Thirty four completed responses from 90 invitees were received in Round 1 of the Delphi; Round 2 involved 23 individuals (response rate 82%). 45% selected a 1-5 Likert scale, 56.5% wanted to use a table (to justify decisions)...

BACKGROUND The pragmatic-explanatory continuum indicator summary version 2 (PRECIS-2) tool has recently been developed to classify randomized clinical trials (RCTs) as pragmatic or explanatory based on their design characteristics. Given that treatment effects in explanatory trials may be greater than those obtained in pragmatic trials, conventional meta-analytic approaches may not accurately a...

BACKGROUND If you want to know which of two or more healthcare interventions is most effective, the randomised controlled trial is the design of choice. Randomisation, however, does not itself promote the applicability of the results to situations other than the one in which the trial was done. A tool published in 2009, PRECIS (PRagmatic Explanatory Continuum Indicator Summaries) aimed to help ...

INTRODUCTION There has been increasing interest in pragmatic trials methodology. As a result, tools such as the Pragmatic-Explanatory Continuum Indicator Summary-2 (PRECIS-2) are being used prospectively to help researchers design randomised controlled trials (RCTs) within the pragmatic-explanatory continuum. There may be value in applying the PRECIS-2 tool retrospectively in a systematic revie...