OBJECTIVE To study the impact of national economic and human development status on patient profiles and outcomes in the setting of acute coronary syndrome (ACS). METHODS We conducted a retrospective analysis of the Targeted Platelet Inhibition to Clarify the Optimal Strategy to Medically Manage Acute Coronary Syndromes trial (TRILOGY ACS) population (51 countries; 9301 patients). Outcome meas...

A capillary zone electrophoresis (CZE) approach was developed for the determination of hexamethylene diisocyanate (HDI) monomer and HDI-based oligomers. A comparison of CZE with high performance liquid chromatography (HPLC) indicates that the CZE separation completely isolates isocyanates from excess solvent, derivatizing reagent and pigment while offering a fivefold increase in sensitivity. Th...

In this study we developed an in vitro exposure model to investigate the effects of hexamethylene diisocyanate (HDI) on human airway epithelial cells at the cellular and molecular level. We used immunofluorescence analysis (IFA) to visualize the binding and uptake of HDI by airway epithelial cell lines (A549 and NCI-NCI-H292) and microarray technology to identify HDI sensitive genes. By IFA, we...

Myrskylä et al. (2009) found that the relationship between the human development index (HDI) and the total fertility rate (TFR) reverses from negative (i.e., increases in HDI are associated with decreases in TFR) to positive (i.e., increases in HDI are associated with increases in TFR) at an HDI level of 0.86. In this article, we show that the reversal in the HDI-TFR relationship is robust to n...

Hexamethylene diisocyanate (HDI) is used widely to manufacture polyurethanes for paints and coatings. It is an irritant and a chemical asthmagen. The U.S. Occupational Safety and Health Administration time-weighted average permissible exposure limit is 5 ppb and the ceiling limit is 20 ppb. We sought to develop a sensitive and specific immuno-bioassay to supplement workplace air monitoring and ...

PURPOSE The aim of this study was to assess the risk factors of prolonged hemodynamic instability (HDI) after carotid angioplasty and stenting (CAS). Herein, a simplified predictive scoring system for prolonged HDI is proposed. MATERIALS AND METHODS Sixty-six patients who had CAS from 2011 to 2016 at a single institution were evaluated. Prolonged HDI was defined as systolic blood pressure >16...

In the recent years, incidence and mortality of cancer, has been increasing in the world (1). Therefore, cancer is one of the major public health problems in many countries (2). The incidence of cancer is different in various countries. Geographical differences in the cancer incidence may be due to different distribution of cancer risk factors in the world. Many of risk factor causes cancer, a ...

The hexamethylene diisocyanate (HDI) contained polyurethane (PU) grafted multi-walled carbon nanotubes (HDI-g-MWNTs) have been synthesized by simple blending method to fabricate thermal conductive nanocomposite. This method shows that HDI-g-MWNTs can improve the interfacial compatibility between HDI-g-MWNTs and matrix. The HDI base PU thermal conductive film (HDI-PU) showed enhanced dispersibil...

BACKGROUND The purpose of this study was to determine whether psychosocial work demands have a different impact on sickness absence and presenteeism in countries with a high vs. countries with a low Human Development Index (HDI). METHODS This article is based on an analysis of the fifth European Working Conditions Survey. We investigated single items as well as complex constructs and indices....

INTRODUCTION The effect of socioeconomic status (SES) on stroke mortality at population level has been controversial. This study explores the association of SES in childhood and adulthood with stroke mortality, as well as variations in this association among countries/regions. METHODS Sex-specific stroke mortality at country level with death registry covering ≥ 70% population was obtained fro...