conclusions serum p and ipth levels were independently associated with et-1 and those may play a role in development of endothelial dysfunction in chronic kidney disease. patients and methods in this cross-sectional study, 46 chronic stable hd patients were selected from nephrology departments of tabriz university of medical sciences affiliated hospitals and classified based on phosphorus (p), ...

Q15080 p40phox Hs R 3P Ellson et al. (2001a); Kanai et al. (2001) P14598 p47phox Hs R 3,4 Ago et al. (2001); Kanai et al. (2001) O60493 SNX3 Hs R 3P Xu et al. (2001a) Q9UNH6 SNX7 Hs R 3P Xu et al. (2001a) P57768 SNX16 Hs R 3P Xu et al. (2001a) Q9BSD1 RGS-PX1 Hs R 3P Zheng et al. (2001) P32912 Vam7 Sc R 3P Cheever et al. (2001); Song et al. (2001); Yu et al. (2001) Q08826 SNX3 Sc R 3P Yu et al. ...

To determine the role of endothelin-1 (ET-1) and its receptors in salt-sensitive hypertension induced by sensory nerve degeneration, selective ET(A) antagonist (ABT-627) and ET(B) antagonist (A-192621) were used. Newborn Wistar rats were given vehicle or 50 mg/kg capsaicin subcutaneously on the first and second days of life. After the weaning period, male rats were divided into eight groups, an...

Endothelin-1 (ET-1) is increased in rats on a high-salt (HS) diet and participates in salt-dependent hypertension. Afferent arterioles (AA) are important for long-term blood pressure control, and therefore we hypothesized that a HS diet would alter their responsiveness to ET-1. Sprague-Dawley rats were fed either a normal-salt (NS; 0.66% NaCl) or HS (8%) diet for 1 wk. Diameters of AA were dete...

High-salt diet is often associated with increases in arterial pressure, and a role for endothelin (ET)-1 in salt-sensitive hypertension has been suggested; however, the vascular mechanisms involved are unclear. We investigated whether ET increases the sensitivity of the mechanisms of vascular contraction to changes in dietary salt intake. Active stress and Ca influx were measured in endothelium...