نتایج جستجو برای: محیط EMB

تعداد نتایج: 76602  

ژورنال: :پاتوبیولوژی مقایسه ای 2007
حامد اهری دکتر قاسم یوسف بیگی دکتر رسول خدابخش شیما قلی زاده سلطانی دکتر سعید نفیسی

تعداد 9 نمونه آلوده، ازمجموع صد نمونه گرفته شده از آ بهای مزارع پرورشآبزیان و طیور ،جهت آزمایش مورد استفاده قرار گرفت که دسته اول جهتپرتودهی اشعه به آزمایشگاه فیزیک هسته ای انتقال یافته بعد از پرتودهی ( توسط منبع تاش سزیوم  cs 137 )به میزان اکتیویته 20 میلی کوری به مدت زمان 6 ساعت مورد تابش قرار گرفتند ) در زمان کمتر از 2 ساعت جهت انجام مراحلکشت به آزمایشگاه انتقال یافتند و دسته دوم بلافاصله در...

2010
Ali Yilmaz Felix Mahfoud Christian Ukena Anastasios Athanasiadis Karin Klingel

Background—Endomyocardial biopsy (EMB) represents the gold standard for diagnosing myocarditis and nonischemic cardiomyopathies. This study focuses on the risk of complications and the respective diagnostic performance of left ventricular (LV), right ventricular (RV), or biventricular EMB in patients with suspected myocarditis and/or cardiomyopathy of unknown origin. Methods and Results—In this...

Journal: :Circulation 2010
Ali Yilmaz Ingrid Kindermann Michael Kindermann Felix Mahfoud Christian Ukena Anastasios Athanasiadis Stephan Hill Heiko Mahrholdt Matthias Voehringer Michael Schieber Karin Klingel Reinhard Kandolf Michael Böhm Udo Sechtem

BACKGROUND Endomyocardial biopsy (EMB) represents the gold standard for diagnosing myocarditis and nonischemic cardiomyopathies. This study focuses on the risk of complications and the respective diagnostic performance of left ventricular (LV), right ventricular (RV), or biventricular EMB in patients with suspected myocarditis and/or cardiomyopathy of unknown origin. METHODS AND RESULTS In th...

Journal: :Antimicrobial agents and chemotherapy 2016
Subramanya Lingaraju Leen Rigouts Aditi Gupta Jongseok Lee Alaine Nyaruhirira Umubyeyi Amy L Davidow Susan German EunJin Cho Ji-Im Lee Sang-Nae Cho Cheon Tae Kim David Alland Hassan Safi

Ethambutol (EMB) resistance can evolve through a multistep process, and mutations in the ubiA (Rv3806c) gene appear to be responsible for high-level EMB resistance in Mycobacterium tuberculosis We evaluated the prevalence of ubiA and embB (Rv3795) mutations in EMB-resistant strains originating from Africa and South Korea. No differences in embB mutation frequencies were observed between strains...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1996
A E Belanger G S Besra M E Ford K Mikusová J T Belisle P J Brennan J M Inamine

The antimycobacterial compound ethambutol [Emb; dextro-2,2'-(ethylenediimino)-di-1-butanol] is used to treat tuberculosis as well as disseminated infections caused by Mycobacterium avium. The critical target for Emb lies in the pathway for the biosynthesis of cell wall arabinogalactan, but the molecular mechanisms for drug action and resistance are unknown. The cellular target for Emb was sough...

2013
Zofia Bakuła Agnieszka Napiórkowska Jacek Bielecki Ewa Augustynowicz-Kopeć Zofia Zwolska Tomasz Jagielski

Ethambutol (EMB) continues to be used as part of a standard drug regimen for the treatment of tuberculosis (TB). Mutations in the embB gene and those within its conserved EMB resistance determining region (ERDR) in particular have repeatedly been associated with resistance to EMB in Mycobacterium tuberculosis. The aim of this study was to examine the mutational "hot spots" in the embB gene, inc...

Journal: :Antimicrobial agents and chemotherapy 1997
S Sreevatsan K E Stockbauer X Pan B N Kreiswirth S L Moghazeh W R Jacobs A Telenti J M Musser

Ethambutol [(S,S')-2,2'-(ethylenediimino)di-1-butanol; EMB], is a first-line drug used to treat tuberculosis. To gain insight into the molecular basis of EMB resistance, we characterized the 10-kb embCAB locus in 16 EMB-resistant and 3 EMB-susceptible genetically distinct Mycobacterium tuberculosis strains from diverse localities by automated DNA sequencing and single-stranded conformation poly...

Journal: :Antimicrobial agents and chemotherapy 2000
S V Ramaswamy A G Amin S Göksel C E Stager S J Dou H El Sahly S L Moghazeh B N Kreiswirth J M Musser

Ethambutol (EMB) is a central component of drug regimens used worldwide for the treatment of tuberculosis. To gain insight into the molecular genetic basis of EMB resistance, approximately 2 Mb of five chromosomal regions with 12 genes in 75 epidemiologically unassociated EMB-resistant and 33 EMB-susceptible Mycobacterium tuberculosis strains isolated from human patients were sequenced. Seventy...

2017
Zhijie Zhang Xinyu Zhao Xiaosong Qin

Pesticide residue inducing cancer-related health problems draw people more attention recently. Emamectin benzoate (EMB) has been widely used in agriculture around the world based on its specificity targets. Although potential risk and the molecular mechanism of EMB toxicity to human liver has not been well-characterized. Unlike well-reported toxicity upon central nervous system, potential genot...

Journal: :Microbiology 2005
Eva Radmacher Kathrin C Stansen Gurdyal S Besra Luke J Alderwick William N Maughan Günter Hollweg Hermann Sahm Volker F Wendisch Lothar Eggeling

Corynebacterium glutamicum is used for the large-scale production of L-glutamate, but the efflux of this amino acid is poorly understood. This study shows that addition of ethambutol (EMB) to growing cultures of C. glutamicum causes L-glutamate efflux at rates of up to 15 nmol min(-1) (mg dry wt)(-1), whereas in the absence of EMB, no efflux occurs. EMB is used for the treatment of Mycobacteriu...

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