In the field of health and medicine, there is a long tradition of collaboration between developing countries and Western nations. These collaborative efforts have embraced teaching, research, and provision of training and personnel, as well as donations of resources and technological help. In the late 1990s, the medical press began to allocate significant space in their journals to the issue of...

An analytic study was conducted on coupled partial differential equations. We formally derived new solitary wave solutions of generalized coupled system of Zakharov-Kuznetsov (ZK) and KdV equations by using modified extended tanh method. The traveling wave solutions for each generalized coupled system of ZK and KdV equations are shown in form of periodic, dark, and bright solitary wave solution...

BACKGROUND Respiratory syncytial virus (RSV) viral load and disease severity associate, and the timing of viral load and disease run in parallel. An antiviral must be broadly effective against the natural spectrum of RSV genotypes and must attain concentrations capable of inhibiting viral replication within the human respiratory tract. OBJECTIVES We evaluated a novel RSV fusion inhibitor, MDT...

Bone development is dynamically regulated by homeostasis, in which a balance between adipocytes and osteoblasts is maintained. Disruption of this differentiation balance leads to various bone-related metabolic diseases, including osteoporosis. In the present study, a primate-specific microRNA (miR-637) was found to be involved in the differentiation of human mesenchymal stem cells (hMSCs). Our ...

BACKGROUND The objective of this study was to investigate the molecular mechanism by which miR-637 interferes with the expression of CDK6, which contributes to the development of pulmonary hypertension (PH) with chronic obstructive pulmonary disease (COPD). MATERIAL AND METHODS We used an online miRNA database to identify CDK6 as a virtual target of miR-637, and validated the hypothesis using l...

سن گلخوار یونجه، Lygus rugulipennis Poppius (Hemiptera: Miridae)، یکی از آفات مهم یونجه در بسیاری نقاط جهان می‌باشد. زیست‌شناسی آزمایشگاهی و پراسنجه‌های جدول زندگی این آفت پنج دمای 25، 5/27، 30، 5/32 35 درجه سلسیوس، رطوبت نسبی 5 ±60 درصد دوره نوری 16 ساعت روشنایی 8 تاریکی مورد بررسی قرار گرفت. قادر به نشوونما سلسیوس نبود. طولانی‌ترین کوتاه‌ترین طول پورگی به‌ترتیب 5/27 (81/13 روز) (08/8 به‌دست آ...

During the construction of the transmissible gastroenteritis virus (TGEV) full-length cDNA clone, a point mutation at position 637 that was present in the defective minigenome DI-C was maintained as a genetic marker. Sequence analysis of the recovered viruses showed a reversion at this position to the original virus sequence. The effect of point mutations at nucleotide 637 was analyzed by rever...

This paper begins a series studying D-modules on the Feigin-Frenkel semi-infinite flag variety from the perspective of the Beilinson-Drinfeld factorization (or chiral) theory. Here we calculate Whittaker-twisted cohomology groups of Zastava spaces, which are certain finite-dimensional subvarieties of the affine Grassmannian. We show that such cohomology groups realize the nilradical of a Borel ...

Irritable bowel syndrome (IBS) is a common disorder mainly characterized by altered bowel habits and visceral pain. In this study, we investigated the role of tachykinin NK1 receptors in the visceral pain response (abdominal muscle contraction) caused by colorectal distention in rabbits previously subjected to colonic irritation, using the selective tachykinin NK1 receptor antagonists TAK-637 [...