OBJECTIVE Leukotriene B4 (LTB4), a potent leukocyte chemoattractant, is known to promote several inflammatory diseases, including atherosclerosis. We sought to determine mechanisms through which LTB4 modulates atherosclerosis in cell lines expressing LTB4 receptors, BLT-1, and in mice deficient in BLT-1 as well as macrophage cell lines derived from BLT-1+/+ and BLT-1-/- mice. METHODS AND RESU...

The Bacillus subtilis genome encodes two multidrug efflux transporters sharing 51% sequence identity: Bmr, described previously, and Blt, described here. Overexpression of either transporter in B. subtilis leads to a similar increase in resistance to ethidium bromide, rhodamine and acridine dyes, tetraphenylphosphonium, doxorubicin, and fluoroquinolone antibiotics. However, Blt differs widely f...

A BLT-set is a set X of q+l points of the generalized quadrangle Q(4, q), q odd, such that no point of Q(4, q) is collinear with more than 2 points of X. BLT-sets are closely related to flocks of the quadratic cone, elation generalised quadrangles and certain translation planes. In this paper we report on the results of computer searches for BLT-sets for odd q ::; 25. We complete the classifica...

Polycrystalline thin films of La-substituted bismuth titanate (BLT) were formed directly on p-type Si(100) substrates by using sol-gel and spin coat methods. The BLT film and interfacial layer between BLT and Si were quantitatively investigated by the X-ray reflectivity method. Also, crystal orientations of sub-100-nm-thick BLT thin films were confirmed by X-ray diffraction using a synchrotron ...

INTRODUCTION Immunodeficient mice engrafted with human immune systems support studies of human hematopoiesis and the immune response to human-specific pathogens. A significant limitation of these humanized mouse models is, however, a severely restricted ability of human B cells to undergo class switching and produce antigen-specific IgG after infection or immunization. METHODS In this study, ...

Bioluminescence tomography (BLT) is a recently developed area in biomedical imaging. The goal of BLT is to quantitatively reconstruct a bioluminescent source distribution within a small animal from optical signals on the surface of the animal body. While there have been theoretical investigations of the BLT problem in the literature, in this paper, we propose a more general mathematical framewo...

A 16-blt oversampllng D/A converter has been designed uslng a 4'th order all-dlgltal noise-shaping loop followed by a 3-blt D/A converter. The 3-blt D/A converter, which employs a novel form of dynamlc element matchlng, achleves hlgh accuracy and long-term stablllty without requlrlng preclslon matchlng of components. The harmonic dlstortlon of the untrimmed monolithic CMOS prototype D/A convert...

Driven by the growing demand for renewable and clean energy, photovoltaic effect of various solar cells materials was investigated conversion light energy into electricity. We modified Bi3.25La0.75Ti3O12 (BLT) Co-doped BLT (Co–BLT) composites with Fe (FeCo–BLT) films to narrow bandgap increase visible absorption, thereby improving efficiency reaction. In this study, Co–BLT thin were fabricated ...

Since the first description of Seasonal Affective Disorder (SAD) by Rosenthal et al. in the 1980s, treatment with daily administration of light, or Bright Light Therapy (BLT), has been proven effective and is now recognized as a first-line therapeutic modality. More recently, studies aimed at understanding the pathophysiology of SAD and the mechanism of action of BLT have implicated shifts in t...