The D-loop region is a hot spot for mitochondrial DNA (mtDNA) alterations, containing two hypervariable segments, HVS-I and HVS-II. In order to identify polymorphic sites and potential genetic background accounting for Hypertrophic CardioMyopathy (HCM) disease, the complete non-coding region of mtDNA from 31 unrelated HCM patients and 45 normal controls were sequenced. The sequences were aligne...

STP-C488 (STP of herpesvirus saimiri [HVS] group C strain 488 [C488]) is the only virus-encoded protein found to associate with cellular ras and activate ras signal transduction pathways. To investigate an important role for ras signal transduction in STP-dependent growth transformation, we constructed recombinant strains of HVS C488 in which the STP-C488 oncogene was replaced with cellular nor...

Computational models of the human visual system (HVS) play an instrumental role in the design and operation of numerous image and video processing algorithms. HVS models have proved beneficial not only for boosting an algorithm’s performance, but also for improving its reliability and robustness to changing conditions. Many processing algorithms operate on images and videos that are meant to be...

Herpesvirus saimiri (HVS) is a gamma herpesvirus with several properties that make it an amenable gene therapy vector; namely its large packaging capacity, its ability to persist as a nonintegrated episome, and its ability to infect numerous human cell types. We used RecA-mediated recombination to develop an HVS vector with a mutated virion protein. The heparan sulphate-binding region of HVS OR...

In this paper two new blind adaptive digital watermarking methods of color images are presented. The adaptability is based on perceptual watermarking which exploits Human Visual System (HVS) models. The first method performs watermark embedding in transform domain of DCT and the second method is based on DWT. Watermark is embedded into transform domain of a chosen color image component in a sel...

The product of open reading frame 14 (orf14) of herpesvirus saimiri (HVS) exhibits significant homology with mouse mammary tumor virus superantigen. orf14 encodes a 50-kDa secreted glycoprotein, as shown previously (Z. Yao, E. Maraskovsky, M. K. Spriggs, J. I. Cohen, R. J. Armitage, and M. R. Alderson, J. Immunol. 156:3260-3266, 1996). orf14 expressed from recombinant baculovirus powerfully ind...

By taking into account the properties and limitations of the human visual system (HVS), images can be more efficiently compressed, colors more accurately reproduced, prints better rendered, to mention a few major advantages. To achieve these goals it is necessary to build a computational model of the HVS. In this paper we give an introduction to the general issue of HVS-modeling and review the ...

BACKGROUND The success of mechanical clot retrieval for acute ischemic stroke may be influenced by the characteristics of the occlusive thrombus. The thrombus can be partly characterized by CT, as the hyperdense vessel sign (HVS) suggests erythrocyte-rich clot whereas fibrin-rich clot may be isodense. We hypothesized that the physical clot characteristics that determine CT density may also dete...