This paper introduces SPar, an internal C++ Domain-Specific Language (DSL) that supports the development of classic stream parallel applications. The DSL uses standard C++ attributes to introduce annotations tagging the notable components of stream parallel applications: stream sources and stream processing stages. A set of tools process SPar code (C++ annotated code using the SPar attributes) ...

Homeostatic plasticity keeps neuronal spiking output within an optimal range in the face of chronically altered levels of network activity. Little is known about the underlying molecular mechanisms, particularly in response to elevated activity. We report that, in hippocampal neurons experiencing heightened activity, the activity-inducible protein kinase Polo-like kinase 2 (Plk2, also known as ...

This paper describes SPAR, a task planner that has been implemented on a PUMA 762. SPAR is capable of formulating manipulation plans to meet specified assembly goals; these manipulation plans include grasping and regrasping operations if they are deemed necessary for successful completion of assembly. SPAR goes beyond the classical AI planners, in the sense that SPAR is capable of solving geome...

In this paper we will give a small introduction to Spar, a programming language for semi-automatic parallel programming. Spar, a Java derivative is being developed as part of the Automap project, which aims to create completely automatic mappings for code and data at either compile time or runtime. We will present how Spar supports task-parallel programming and how it interacts with the user or...

The PSD-95/SAP90 family of scaffold proteins organizes the postsynaptic density (PSD) and regulates NMDA receptor signaling at excitatory synapses. We report that SPAR, a Rap-specific GTPase-activating protein (RapGAP), interacts with the guanylate kinase-like domain of PSD-95 and forms a complex with PSD-95 and NMDA receptors in brain. In heterologous cells, SPAR reorganizes the actin cytoskel...

The Standardized Plant Analysis Risk-Human Reliability Analysis (SPAR-H) method has proved to be a reliable, easy-to-use method for human reliability analysis. Calculation of human error probability (HEP) rates is especially straightforward, starting with pre-defined nominal error rates for cognitive vs. action oriented tasks, and incorporating performance shaping factor (PSF) multipliers upon ...

Here we introduce a quantitative structure-driven computational domain-fusion method, which we used to predict the structures of proteins believed to be involved in regulation of the subtilin pathway in Bacillus subtilis, and used to predict a protein-protein complex formed by interaction between the proteins. Homology modeling of SpaK and SpaR yielded preliminary structural models based on a b...

The Standardized Plant Analysis Risk (SPAR) Model Development Program has played an integral role in the Accident Sequence Precursor (ASP) Program analysis of operating events. In a complementary fashion, one of the objectives of the ASP Program is to use plant operating experience results and insights for feedback to the SPAR models, as well as to licensee probabilistic risk assessment (PRA) m...

The National Library of France (BnF) has recently implemented a new module for its Scalable Preservation and Archiving Repository (SPAR) to set up preservation strategies based on formats, agents, workflows, tools and tests, and managed asreference packages in the Archive. This module aims to fulfill an objective: for SPAR to be fully selfdocumented. Formats, agents and workflows are formally d...