Accumulation of infectious Plasmodium sporozoites in Anopheles spp. salivary glands marks the final step of the complex development of the malaria parasite in the insect vector. Sporozoites are formed inside midgut-associated oocysts and actively egress into the mosquito hemocoel. Traversal of the salivary gland acinar cells correlates with the sporozoite's capacity to perform continuous glidin...

Substrate-binding protein-dependent secondary transporters are widespread in prokaryotes and are represented most frequently by members of the tripartite ATP-independent periplasmic (TRAP) transporter family. Here, we report the membrane reconstitution of a TRAP transporter, the sialic acid-specific SiaPQM system from Haemophilus influenzae, and elucidate its mechanism of energy coupling. Uptak...

In previous work on Philadelphia, SIAP found that nonprofit arts and cultural organizations tended to concentrate in economically and ethnically diverse neighborhoods. This paper uses data on for-profit cultural firms to document whether they too cluster in diverse neighborhoods or if they have a different logic of agglomeration. The paper uses two data sets for the five-county Philadelphia reg...

The requirement of integrating, sharing and reusing legislative information is a research issue gaining priority for governments and institutions. The legal world is complex, heterogeneous and wide in scope. Therefore, we find convenient to define ontologies as a tool to decrease this complexity inherent to the legal domain. This paper is based on the Parliamentary Integrated Management System ...

In this research, using technique for order-preference by similarity to ideal solution (TOPSIS) index, drought phenomenon is determined and ranked. For this purpose, using 5 atmospheric elements including temperature, wind, precipitation days, annual precipitation, precipitation concentration index (PCI), droughts occurred in Shiraz station for 20-year statistical period (1983-2003) have been d...

During 2008, SIAP collaborated with the Americans for the Arts’ Animating Democracy project on a review of the literature on civic engagement and the arts. Based on that review, SIAP considered the theoretical and methodological issues and developed a comprehensive strategy by which policymakers, researchers, and practitioners could improve evidence and advance understanding of the civic impact...

This policy brief—a product of the SIAP Culture and Community Revitalization Collection, in collaboration with Reinvestment Fund---uses existing research on urban culture and community arts to make a case for culture-based neighborhood revitalization. The brief defines and illustrates "natural" cultural districts, highlights the synergy of social diversity and cultural engagement, and draws les...