نتایج جستجو برای: روش MRGC
تعداد نتایج: 369590 فیلتر نتایج به سال:
OBJECTIVE This study is to investigate the role of Mas-related gene (Mrg) C in the pathogenesis and treatment of bone cancer pain (BCP). METHODS BCP mouse model was established by osteosarcoma cell inoculation. Pain-related behaviors were assessed with the spontaneous lifting behavior test and mechanical allodynia test. Expression levels of MrgC, Gi, and NR2B in the spinal cord were detected ...
This study was aimed to investigate the mechanisms of the modulation effect of activation of spinal Mas-related gene C (MrgC) receptors on hyperalgesia induced by intraplantar (i.pl.) injection of (Tyr6)-γ2-MSH-6-12 (MSH) or complete Freund's adjuvant (CFA). Paw withdrawal latency test and immunohistochemistry were used to observe the effect of intrathecal (i.t.) administration of MSH or BAM8-2...
We address the problem of the factors contributing to a peak color trend of old metal-rich globular cluster (MRGC) populations with mass of their hosts, early-type galaxies and spheroidal subsystems of spiral ones (spheroids). The colormass trend is often converted to a metallicity-mass trend under the assumption that age effects are small or negligible. While direct estimates of the ages of MR...
Human sensory neuron-specific mas-related gene X1 receptors (hMrgX1s) belong to the superfamily of G protein-coupled receptors (GPCRs), bind cleavage products of pro-enkephalin with high affinity, and have been suggested to participate in pain sensation. Murine or rat MrgC receptors exhibit high similarities with hMrgX1 in terms of expression pattern, sequence homology, and binding profile. The...
Mas oncogene-related G protein-coupled receptor C (MrgC) is unequally expressed in sensory ganglia and has been shown to modulate pathologic pain. This study investigated the mechanism underlying the effect of MrgC receptors on inflammatory pain. Intrathecal administration of the selective MrgC receptor agonist bovine adrenal medulla 8-22 (BAM8-22) (30 nmol) inhibited complete Freund's adjuvant...
The Mas-related genes (Mrgs) comprise a family of >50 G protein-coupled receptors (GPCRs), many of which are expressed in specific subsets of nociceptive sensory neurons in mice. In contrast, humans contain a related but nonorthologous family of genes, called MrgXs or sensory neuron-specific receptors, of which many fewer appear to be expressed in sensory neurons. To determine whether the diver...
OBJECTIVE We analysed the efficacy and toxicity of irinotecan, leucovorin and 5-fluorouracil (FOLFIRI) chemotherapy as second-line treatment for metastatic or relapsed gastric cancer (MRGC) in a clinical practice setting. Factors to select patients who may benefit from salvage chemotherapy was also analysed. METHODS Patients with MRGC with progression on or within 6 months after discontinuing...
زون تولیدی در توالی یک چاه، شامل فواصلی از سازند مخزنی است که دارای بالاترین میزان تجمع هیدروکربن است.در مطالعة حاضر که در توالی یک مخزن گازی کربناته صورت گرفت، زون های تولیدی با دو روش کاملا متفاوت مشخص شدند. در روش اول که عموماّ از این روش برای تعیین زون های تولیدی استفاده می شود، با استفاده از تعیین حد برش برای دو پارامتر پتروفیزیکی، تخلخل مؤثرو اشباع آب مؤثر این فواصل مشخص شد و در روش دوم با...
OBJECTIVE Melanopsin retinal ganglion cells (mRGCs) are photoreceptors driving circadian photoentrainment, and circadian dysfunction characterizes Alzheimer disease (AD). We investigated mRGCs in AD, hypothesizing that they contribute to circadian dysfunction. METHODS We assessed retinal nerve fiber layer (RNFL) thickness by optical coherence tomography (OCT) in 21 mild-moderate AD patients, ...
هدف از این پژوهش، معرفی بهترین روش خوشه سازی جهت تعیین رخساره های الکتریکی مخزنی در چاه های فاقد مغزه می باشد. تعیین رخساره های الکتریکی در اصل یک روش قطعی یا تحلیلی برای دسته بندی داده های چاه نگارهای پتروفیزیکی است که می تواند نشان دهنده تغییر ویژگی های زمین شناسی یا مخزنی باشد. رخساره های الکتریکی بر مبنای خوشه سازی داده ها تعریف می شود. مبنای خوشه سازی، قرار دادن داده های نمودارهای پتروفیزی...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید