با توجه به اهمیت حذف یون استرانسیم موجود در پساب‌­های هسته­ای، کار حاضر ضمن سنتز لیگاندهای هیدروکسی بنزآلدهید پروپیل تری اتوکسی سیلان (Si-HL3(EtO)) و پیریدیل متیلیدین (Si-L3(EtO)) بررسی خصوصیات نانو ذرات سیلیکای اصلاح ­شده این لیگاندها ­عنوان جاذب جامد از محلول آبی پرداخته شد پارامترهایی مانند pH، زمان، جرم جاذب، دما یون‌­های مزاحم مورد آزمایش قرار گرفت. رفتار جذبی جاذ­ب‌­ها نشان داد سطح توانای...

BACKGROUND Insect baculovirus-produced Human immunodeficiency virus type 1 (HIV-1) Gag virus-like-particles (VLPs) stimulate good humoral and cell-mediated immune responses in animals and are thought to be suitable as a vaccine candidate. Drawbacks to this production system include contamination of VLP preparations with baculovirus and the necessity for routine maintenance of infectious baculov...

We have evaluated the immunogenicity and protective efficacy of rotavirus subunit vaccines administered by mucosal routes. Virus-like particles (VLPs) produced by self-assembly of individual rotavirus structural proteins coexpressed by baculovirus recombinants in insect cells were the subunit vaccine tested. We first compared the immunogenicities and protective efficacies of VLPs containing VP2...

The recognition that rotaviruses are the major cause of life-threatening diarrheal disease and significant morbidity in young children has focused efforts on disease prevention and control of these viruses. Although the correlates of protection in children remain unclear, some studies indicate that serotype-specific antibody is important. Based on this premise, current live attenuated reassorta...

BACKGROUND Eleven new human polyomaviruses (HPyVs) have been identified in the last decade. Serological studies show that these novel HPyVs sub-clinically infect humans at an early age. The routes of infection, entry pathways, and cell tropism of new HPyVs remain unknown. VP1 proteins of polyomaviruses can assembly into virus-like particles (VLPs). As cell culturing systems for HPyV are current...