aus Córdoba (Argentinien) aus Córdoba (Argentinien) aus Córdoba (Argentinien) aus Córdoba (Argentinien) Abstract Abstract Abstract Abstract Hippocampal oscillations and neuronal plasticity are involved in both cognitive functions and pathological processes. In vivo, Sharp wave-ripple (SPW-Rs) consisting of slow field potential transients with superimposed ripples by ca. 200 Hz oscillations are ...

Sharp wave ripples (SPW-Rs) represent the most synchronous population pattern in the mammalian brain. Their excitatory output affects a wide area of the cortex and several subcortical nuclei. SPW-Rs occur during "off-line" states of the brain, associated with consummatory behaviors and non-REM sleep, and are influenced by numerous neurotransmitters and neuromodulators. They arise from the excit...

Network oscillations of different frequencies, durations and amplitudes are hypothesized to coordinate information processing and transfer across brain areas. Among these oscillations, hippocampal sharp wave-ripple complexes (SPW-Rs) are one of the most prominent. SPW-Rs occurring in the hippocampus are suggested to play essential roles in memory consolidation as well as information transfer to...

Sharp-wave ripples (SPW-Rs) in the hippocampus are implied in memory consolidation, as shown by observational and interventional experiments. However, the mechanism of their generation remains unclear. Using two-dimensional silicon probe arrays, we investigated the propagation of SPW-Rs across the hippocampal CA1, CA2, and CA3 subregions. Synchronous activation of CA2 ensembles preceded SPW-R-r...

OBJECTIVES To evaluate the relationship between exposure to gaseous air pollutants (ozone [O3], carbon monoxide [CO], nitrogen dioxide [NO2], and sulfur dioxide [SO2]) socioeconomic status and the prevalence of symptoms of asthma, rhinitis and atopic eczema in adolescents. SUBJECTS AND METHODS A sample of 16 209 adolescents from São Paulo West (SPW), São Paulo South (SPS), Santo André (SA), C...

Memory formation is associated with the generation of transiently stable neuronal assemblies. In hippocampal networks, such groups of functionally coupled neurons express highly ordered spatiotemporal activity patterns which are coordinated by local network oscillations. One of these patterns, sharp wave-ripple complexes (SPW-R), repetitively activates previously established groups of memory-en...

Sharp-wave-ripple (SPW-R) complexes are believed to mediate memory reactivation, transfer, and consolidation. However, their underlying neuronal dynamics at multiple scales remains poorly understood. Using concurrent hippocampal local field potential (LFP) recordings and functional MRI (fMRI), we study local changes in neuronal activity during SPW-R episodes and their brain-wide correlates. Ana...

Given a Banach space X, denote by SPw(X) the set of equivalence classes of spreading models of X generated by normalized weakly null sequences in X. It is known that SPw(X) is a semilattice, i.e., it is a partially ordered set in which every pair of elements has a least upper bound. We show that every countable semilattice that does not contain an infinite increasing sequence is order isomorphi...