BACKGROUND Resection of malignancies in the head and uncinate process of the pancreas (Whipple procedure) using a robotic approach is emerging as a surgical option. Although several case series of the robotic Whipple procedure have been reported, detailed descriptions of operative techniques and a clear pathway for adopting this technology are lacking. METHODS We present a focused review of t...

In 1907, when the first case of Whipple disease was described by George Whipple, the clinical presentation of the disease, although not considered to be of infectious origin, already included cough and diarrhea [1]. This index patient had a chronic form of the disease, coined here as lateonset Whipple disease. During the past century, Whipple disease has been considered to be a rare and chronic...

INTRODUCTION Whipple disease is a rare systemic infection caused by Tropheryma whippelii that usually manifests with joint pain, weight loss, diarrhoea and abdominal pain. However, in some cases the infection may involve other organs and tissues. CASE PRESENTATION We report on a 44-year-old man with Whipple disease which led to renal amyloidosis and end-stage renal failure. In this case, the ...

The Whipple collaboration pioneered the Imaging Atmospheric Cherenkov Technique (IACT) for the detection of Very High Energy (VHE) gamma rays. The Whipple 10 m gamma-ray telescope was located at the Fred Lawrence Whipple Observatory in Southern Arizona in the United States. The predecessor to VERITAS (Very Energetic Radiation Imaging Telescope Array System), this telescope was in operation from...

We tested 53 fixed duodenal biopsy samples from 25 patients with Whipple disease for the presence Giardia and 6 fresh duodenal biopsy samples for Giardia duodenalis DNA by polymerase chain reaction (PCR). We also used histological examination and PCR assay to determine the prevalence of G. duodenalis in duodenal biopsy samples from 150 control patients without Whipple disease. Three of 25 patie...

Whipple disease is a rare, chronic multisystem disease associated with the recently characterized organism Tropheryma whippelii. Extraintestinal manifestation involving the central nervous system, heart, and joints occasionally occurs. Involvement of the abdominal lymph nodes, especially the mesenteric and periaortic nodes, is not uncommon. However, peripheral lymphadenopathy as the sole clinic...