نتایج جستجو برای: جراحی mohs
تعداد نتایج: 15070 فیلتر نتایج به سال:
برای درمان ملانوم بدخیم روش های جراحی مختلفی وجود دارد. این روش ها غالباً با محدودیت هایی در به دست آوردن حاشیه غیردرگیر در عین دستیابی به نتیجه ای مناسب از نظر زیبایی همراه اند. این مقاله، مروری کوتاه بر استفاده از تکنیک های ساده و هم چنین روش میکروگرافیک mohs در درمان جراحی ملانوم بدخیم است.
کارسینوم سلول بازال اولین و شایع ترین سرطان در ایران و جهان است و در آینده، شیوعی برابر با کل سرطان های دیگر خواهد داشت. مسیر سیگنالینگ hedgehog (hh) در بیماری زایی این سرطان نقش به سزایی دارد. به طوری که جهش در ژن ptch و smo عامل حدود 75% تا 95% از کل موارد کارسینوم سلول بازال اسپورادیک و اغلب کارسینوم سلول های بازال ارثی را دربرمی گیرند. امروزه، گزینه های درمانی متعددی برای درمان این نوع سرطا...
BACKGROUND Processing multiple tissue sections in large Mohs cases is time consuming and labor intensive. OBJECTIVE To present innovative laboratory techniques to facilitate processing of large Mohs cases. METHODS A method for processing a large dermatofibrosarcoma protuberans Mohs case is outlined. RESULTS Modifications in tissue processing and equipment employed in a large Mohs case are...
There is an enormous amount of literature pertaining to the subject of Mohs surgery, ranging from its various indications to therapeutic results. One constant limiting factor in this body of knowledge, however, is the scarcity of randomized, controlled studies comparing Mohs surgery with other effective therapeutic modalities. Obviously, it is hard to gather solid scientific evidence in favor o...
Mohs surgery is considered ideal treatment for many types of skin cancers. Developed by Dr Frederic Edward Mohs (1910-2002), Mohs surgery allows all surgical margins to be viewed microscopically, ensuring no cancer cells go unremoved, yet it failed to achieve immediate acceptance when first introduced in the 1940s. A catalyst to the widespread acceptance of Mohs surgery occurred with the work o...
BACKGROUND The conventional technique for cancer resection margin analysis studies only 0.1% of the surgical margins. Complete frozen section margins - also known as Mohs margins - allows for analysis of 100% of the surgical margins. METHODS The objective of our study is to compare oral cavity cancer loco-regional recurrence rates when treated by total frozen sections technique (Total Mohs ma...
Multiple surgical methods are available for the management of malignant melanoma. Often, these methods have limitations in terms of the ability of obtaining margin clearance in the context of an appropriate cosmetic outcome. This article, briefly reviews the use of different simple and excisional techniques as well as that of Mohs micrographic in the surgical management of malignant melanomas
BACKGROUND Mohs surgical technique allows a full view of surgical margins and has a reported cure rate approaching 100%. METHOD A survey amongst Mohs surgeons was performed to assess operator technique. In addition, an animated clay model was constructed to identify and quantify tissue movement seen during the processing of Mohs surgical specimens. RESULTS There is variability in technique ...
OBJECTIVE To compare the cost and margin adequacy of Mohs micrographic surgery (Mohs) and traditional surgical excision (TSE) for the treatment of facial and auricular nonmelanoma skin cancer (NMSC). DESIGN Prospective cost analysis with each patient serving as his or her own control. SETTING Study was performed from 1999 to 2001 at the University of Connecticut dermatology clinic, a tertia...
Mohs micrographic surgery is applied as the primary method of treatment for various cutaneous neoplasms. Many other methods that are modified applications of Mohs micrographic surgery have also been suggested. We introduce a technique, which is a modified vertical method of Mohs micrographic surgery using the double-bladed scalpel.
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