Ro 25-1392 [Ac-Glu8,OCH3-Tyr10,Lys12,Nle17,Ala19,A sp25,Leu26,-Lys27,28-vasoactive intestinal peptide(cyclo 21-25)] is a cyclic peptide analog of vasoactive intestinal peptide (VIP) that potently exerts cellular effects typical of VIP. The selectivity of Ro 25-1392 for type I (VIPR1) and type II (VIPR2) VIP receptors was investigated first in competitive binding studies using Chinese hamster ov...

Tamoxifen (Tam) is a selective estrogen receptor modulator used to inhibit breast tumor growth. Tam can be directly N-glucuronidated via the tertiary amine group or O-glucuronidated after cytochrome P450–mediated hydroxylation. In this study, the glucuronidation of Tam and its hydroxylated and/or chlorinated derivatives [4-hydroxytamoxifen (4OHTam), toremifene (Tor), and 4-hydroxytoremifene (4O...

Y. Zuo***, Y. N. Wang*, Y. Zhang**, Z. L. Shen**, Z. S. Chen**, J. Chen**, Q. Y. Xie** *College of Electric and Information Technology, Hunan University, South Lushan Road 1, 410082 Hunan, P. R. China, E-mail: [email protected] **Key Laboratory of Regenerative Energy Electric-Technology of Hunan Province, Changsha University of Science and Technology, Chiling Road 45, 410114 Hunan, P. R. China...

Before an enteropathogen binds to the small bowel, it must interact with the small-bowel mucus (SBM) layer. To determine whether this interaction involves specific binding of diarrheagenic Escherichia coli, we used a quantitative assay with labeled, purified rabbit SBM. Binding of SBM from an adult rabbit was significantly greater to strain 162, an agglutinating E. coli strain, than it was to R...

Right © 2010 by the Infectious Diseases Society of America; This is a pre-copyediting, author-produced PDF of an article accepted for publication in Clinical infectious diseases following peer review. The definitive publisher-authenticated version Clinical infectious diseases, 51(12), pp.1392-1394; 2010 is available online at: http://cid.oxfordjournals.org/content/51/12/1392.full. NAOSITE: Naga...