Infectious bovine keratoconjunctivitis (IBK) is one of the most economically important diseases in preweaned calves. This study examined the health records of 45,497 calves over a 20-yr period to determine environmental and genetic factors influencing the incidence of IBK. Three data sets were analyzed with an animal model. The first data set (n = 41,986) evaluated environmental factors and gen...

Infectious bovine keratoconjunctivitis (IBK), also known as pinkeye, is characterized by damage to the cornea and is an economically important, lowly heritable, categorical disease trait in beef cattle. Scores of eye damage were collected at weaning on 858 Angus cattle. SNP genotypes for each animal were obtained from BovineSNP50 Infinium-beadchips. Simultaneous associations of all SNP with IBK...

Moraxella bovoculi is a recently described bacterium that is associated with infectious bovine keratoconjunctivitis (IBK) or "pinkeye" in cattle. In this study, closed circularized genomes were generated for seven M. bovoculi isolates: three that originated from the eyes of clinical IBK bovine cases and four from the deep nasopharynx of asymptomatic cattle. Isolates that originated from the eye...

Infectious bovine keratoconjunctivitis (IBK) is an acute disease caused by Moraxella bovis (Mb). Several factors may predispose animals to an IBK outbreak; one commonly observed is infection with bovine herpes virus type 1 (BHV-1). The aim of this study was to investigate the dynamics of BHV-1 virus infection and its relation with clinical cases of IBK in weaned calves from a beef herd with a h...

Infectious bovine keratoconjunctivitis is a disease that affects many herds in the US, however, the epidemiology of the disease is complicated and control is frustrating for many producers. This article discusses putative causes of IBK and approaches to understanding the causes of success and apparent failure in IBK control programs.

BACKGROUND Infectious bovine keratoconjunctivitis (IBK) is the most common ocular disease that affects cattle throughout the world and it has a very significant economic impact. IBK is caused by members of the genus Moraxella and therapeutic and preventive measures have shown limited success. Vaccines, most of them chemically inactivated bacterins, generally induce a limited protection. METHO...

Introduction Infectious bovine keratoconjunctivitis (IBK) is caused by a Gram-negative bacterium, Moraxella bovis. It is characterised by acute contagious ophthalmia and it spreads rapidly among cattle in a herd. M. bovis is generally present on the mucous membranes of healthy animals and is considered to be an opportunistic pathogen (Quinn et al., 1994; Gyles and Thoen, 1993). The bacterium is...

The contribution of the large conductance, Ca2+-modulated, voltage-gated K+ channel current, IBK, to the total current during an action potential (AP) from suprachiasmatic nucleus (SCN) neurons is described using a novel computational approach. An experimental recording of an SCN AP and the corresponding AP-clamp recording of IBK from the literature were both digitized. The AP data set was appl...

Introduction. Moraxella bovoculi is frequently isolated from the eyes of cattle with infectious bovine keratoconjunctivitis (IBK; pinkeye). As M. bovis, which has been causally linked to IBK, expresses an RTX (repeats in structural toxin) cytotoxin that related bovis cytotoxin. Pilin, another pathogenic factor , required for corneal attachment. Seven antigenically distinct pilin serogroups have...