nvt

OBJECTIVE Extensive WHO collaborative studies were performed to evaluate the suitability of transgenic mice susceptible to poliovirus (TgPVR mice, strain 21, bred and provided by the Central Institute for Experimental Animals, Japan) as an alternative to monkeys in the neurovirulence test (NVT) of oral poliovirus vaccine (OPV). METHODS Nine laboratories participated in the collaborative study...

nvt

nvt

The wetlands on the quartz sands aeolian sheet make up one of ecosystems most recognized and important Doñana National Park Biological Reserve (South Spain). More than 650 temporal small-lakes have been surveyed in abundant sand depressions sheet, are a hydro-geomorphological dune-small-lake system. This paper studies pedological diversity around Navazo del Toro (NVT) wetland, biggest small-lak...

BACKGROUND This study evaluated the impact of age and pneumococcal vaccination on the density of pneumococcal nasopharyngeal carriage. METHODS A cluster-randomized trial was conducted in rural Gambia. In 11 villages (the vaccine group), all residents received 7-valent pneumococcal conjugate vaccine (PCV-7), while in another 10 villages (the control group), only children <30 months old or born...

BACKGROUND Since the use of pneumococcal conjugate vaccines PCV7 and PCV13 in children became widespread, invasive pneumococcal disease (IPD) has dramatically decreased. Nevertheless, there has been a rise in incidence of Streptococcus pneumoniae non-vaccine serotypes (NVT) colonising the human nasopharynx. Nasopharyngeal colonisation, an essential step in the development of S. pneumoniae-induc...