Successful completion of cytokinesis relies on addition of new membrane, and requires the recycling endosome regulator Rab11, which localizes to the midzone. Despite the critical role of Rab11 in this process, little is known about the formation and composition of Rab11-containing organelles. Here, we identify the phosphatidylinositol (PI) 4-kinase III beta four wheel drive (Fwd) as a key regul...

The loading of free wheel diodes (FWD) and IGBTs in the power modules of a Voltage Source Converter (VSC) are investigated. In converter duty, the FWD is utilized more then the IGBT. Presently, most FWD’s in power modules are optimized for inverter duty. This practice tends to undersize the FWD from a converter viewpoint. This design philosophy is examined in the paper. For this purpose, the or...

This study evaluates the back calculation of stiffness of a pavement section on Interstate 40 (I-40)in New Mexico through numerical analysis. Falling Weight Deflectometer (FWD) test has been conducted on a section on I-40. Layer stiffness of the pavement has been backcalculated by a backcalculation software, ELMOD, using the FWD test data. Commercial finite element software, ABAQUS, has been us...

CHOREO: Ron & Georgine Woolcock, 5326 Berger Dr SE, Olympia, WA 98513 TELEPHONE: 360-456-2056 E-MAIL: [email protected] MUSIC: “If I Had To Do It All Over Again” by Roy Clark, Varese Vintage CD “Roy Clark Greatest Hits” Track 13. D/L available from Internet. RHYTHM: Two Step PHASE: II TIME/SPEED: 2:37/100% FOOTWORK: Opposite, directions for man except where noted. DATE: June, 2007 SEQUENCE...

Rab11 is a small GTPase that regulates several aspects of vesicular trafficking. Here, we show that Rab11 accumulates at the cleavage furrow of Drosophila spermatocytes and that it is essential for cytokinesis. Mutant spermatocytes form regular actomyosin rings, but these rings fail to constrict to completion, leading to cytokinesis failures. rab11 spermatocytes also exhibit an abnormal accumul...

BACKGROUND Although there is considerable research in the field of fasting and fluid restriction, little is known about the impact of food and water deprivation (FWD) on body circumferences and vital parameters. METHODS During 5 days of FWD in 10 healthy adults, hemodynamic, metabolic, and renal parameters, such as weight, 5 circumferences at neck, waist, hip, chest at axilla, chest at nipple...

Phosphorylation of the Neurospora circadian clock protein FREQUENCY (FRQ) promotes its degradation through the ubiquitin-proteasome pathway. Ubiquitination of FRQ requires FWD-1 (F-box/WD-40 repeat-containing protein-1), which is the substrate-recruiting subunit of an SCF (SKP/Cullin/F-box)-type ubiquitin ligase. In the fwd-1 mutant strains, FRQ degradation is defective, resulting in the accumu...