نتایج جستجو برای: β2-microglobulin

تعداد نتایج: 9355  

Journal: :acta medica iranica 0
omid aminian center for research on occupational disease, tehran university of medical sciences, tehran, iran. saeid eftekhari center for research on occupational disease, tehran university of medical sciences, tehran, iran. maria mazaheri job fit health group, australia. seyed akbar sharifian department of occupational medicine, school of medicine, tehran university of medical sciences, tehran, iran. khosro sadeghniiat-haghighi center for research on occupational disease, tehran university of medical sciences, tehran, iran.

welding is a process in which two or more metals are attached by the use of heat and, in some cases, pressure. direct exposure and inhalation of welding fumes causes acute and chronic side effects in humans. kidney damage is one of these important side effects. β2 microglobulin is an 11.8 kilodalton protein and levels increase in the case of some inflammatory and viral diseases, or kidney malfu...

Journal: :Journal of Biosciences and Medicines 2023

Introduction: β2-microglobulin and prolactin are medium-molecular-weight toxins. We believe that the rate of removal these molecules, using filters with two different surfaces, in post- pre-dilution haemodiafiltration, will be interest to literature. Methods: studied, 12 haemodialyzed patients, those, filter surface 2.5 m2 (Group A) or 2.1 B) post-dilution a C). Results: Satisfactory (best post...

برزی, فرناز, شجری, زهرا, شریفی, فرانک, پیرانی, سولماز,

Background and Objective: Post-transplant diabetes mellitus (PTDM) is one of the problems occurring after kidney transplantation. This study was designed to detect the probable relationship between the glucose intolerance and serum and urinary concentrations of β2-microglobulin as well as their value to predict acute rejection of the transplant. Materials and Methods: In this cohort study, 40 p...

2014
Xu Zeng Deloar Hossain David G Bostwick Guillermo A Herrera Ping L Zhang

Objective. After filtration through glomeruli, β2-microglobulin is reabsorbed in proximal tubules. Increased urinary β2-microglobulin indicates proximal tubule injury and measurement of β2-microglobulin in urine is useful to determine the source of renal injury. Kidney injury molecule-1 (KIM-1) has been characterized as a selective proximal tubule injury marker. This study was designed to evalu...

2015
Tiago Koppe Filippo Vairo Matheus Camargo Livia Paskulin Liane Daudt Ida V. Schwartz

β2-Microglobulin is the major prognostic factor in multiple myeloma, a known comorbidity of Gaucher disease. We evaluated herein serum β2-microglobulin levels of 31 type 1 Gaucher patients; for 8/31 patients, pre- and post-treatment comparisons were made. Thirteen patients (on treatment = 6) had high levels of β2-microglobulin, and showed higher chitotriosidase activity and Severity Score Index...

Journal: :basic and clinical cancer research 0
ramya rajendran molecular diagnosis and drug discovery laboratory, department of biotechnology, school of life sciences, karpagam university, coimbatore, tamilnadu, india sudha sellappa associate professor

background: oral squamous cell carcinoma (oscc) is one of the most common malignant tumors. its incidence is rated as one among the highest in the world and the use of tobacco in various forms is increasingly associated with the cause of oscc. in oral cancer the study of tumor markers have been limited and several tumor makers with clinical promise needs further evaluation. methods: present stu...

2016
Hossain Bostwick Herrera Ballester

domain of the immunoglobulin molecule [3]. β2-microglobulin forms the invariant light chain portion of major histocompatibility complex (MHC) class I molecules [4-6], which can be found on the membrane of all nucleated cells [7]. Thus, cellular membrane turnover is the main source of serum β2-microglobulin [3]. Because of its small size, β2-microgloUrinary β2-Microglobulin is a Sensitive Indica...

Journal: :acta medica iranica 0
afshin safaei asl department of pediatrics, school of medicine, guilan university of medical sciences, guilan, iran. shohreh maleknejad department of pediatrics, school of medicine, guilan university of medical sciences, guilan, iran. abtin heidarzadeh department of pediatrics, school of medicine, guilan university of medical sciences, guilan, iran. yazdan ghandi department of pediatrics, school of medicine, guilan university of medical sciences, guilan, iran.

to find if some indices have predictive value for renal complications. we conducted a cross sectional and included 80 patients with the age ranged 5-17 years, all with the proven diagnosis of β-thalassemia major. a urine and 5 ml of blood sample were obtained from all of the cases. biochemical indices such as serum levels of creatinine, na, mg, hb, and ferritin and also urine levels of na, mg, ...

2017
Sara Raimondi Riccardo Porcari P. Patrizia Mangione Guglielmo Verona Julien Marcoux Sofia Giorgetti Graham W. Taylor Stephan Ellmerich Maurizio Ballico Stefano Zanini Els Pardon Raya Al-Shawi J. Paul Simons Alessandra Corazza Federico Fogolari Manuela Leri Massimo Stefani Monica Bucciantini Julian D. Gillmore Philip N. Hawkins Maurizia Valli Monica Stoppini Carol V. Robinson Jan Steyaert Gennaro Esposito Vittorio Bellotti

Systemic amyloidosis is caused by misfolding and aggregation of globular proteins in vivo for which effective treatments are urgently needed. Inhibition of protein self-aggregation represents an attractive therapeutic strategy. Studies on the amyloidogenic variant of β2-microglobulin, D76N, causing hereditary systemic amyloidosis, have become particularly relevant since fibrils are formed in vi...

2014
Changhoon Yoo Dok Hyun Yoon Cheolwon Suh

Beta-2 microglobulin is synthesized in all nucleated cells and forms the light chain subunit of the major histocompatibility complex class I antigen. Despite its potential role as a convenient and non-invasive prognostic indicator in malignant lymphomas, the influence of serum β2 microglobulin is currently underestimated, and therapeutic decision making is rarely affected by this marker. Recent...

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