hla-g is normally expressed on human trophoblast cells. it is a non-classical mhc molecule class i b. the role of hla-g in diabetic type 1 is not known. we investigated the role of ifn-β in induction hla-g expression on the monocyte derived dendritic cells (dc) in diabetes type 1. treatment of dendritic cell with ifn-β in vitro from diabetic patients (n=20) and normal subjects (n=20) resulted t...

avila and molina [1] introduced the notion of generalized weak structures which naturally generalize minimal structures, generalized topologies and weak structures and the structures α(g),π(g),σ(g) and β(g). this work is a further investigation of generalized weak structures due to avila and molina. further we introduce the structures ro(g) and rc(g) and study the properties of the structur...

during antigen capture and processing, mature dendritic cells (dc) express large amounts of peptide-mhc complexes and accessory molecules on their surface. we investigated the role of ifn-β in induction hla-g expression on the monocyte derived dc and cytokine profile in diabetes type 1. we accomplished secretary pattern and total cytokine production of the th1 cytokine (il-2, γifn) and th2 cyto...

a group is called morphic if for each normal endomorphism α in end(g),there exists β such that ker(α)= gβ and gα= ker(β). in this paper, we consider the case that there exist normal endomorphisms β and γ such that ker(α)= gβ and gα = ker(γ). we call g quasi-morphic, if this happens for any normal endomorphism α in end(g). we get the following results: g is quasi-morphic if and only if, for any ...

Avila and Molina [1] introduced the notion of generalized weak structures which naturally generalize minimal structures, generalized topologies and weak structures and the structures α(g),π(g),σ(g) and β(g). This work is a further investigation of generalized weak structures due to Avila and Molina. Further we introduce the structures ro(g) and rc(g) and study the properties of the structures r...

abstract β-thalassemia major (β –tm) is the most common thalassemia severe phenotype among iranians. in recent years, molecular understanding of pathogenesis of β –tm has provided a great opportunity regarding diagnostic issues. creating comprehensive molecular databases provides highly sensitive diagnostic tools for β –tm and effective prenatal diagnosis (pnd) molecular screening tests. despit...

introduction: beta thalassemia is the most common inherited bloody disorder, affecting synthesis of the beta globin chain of hemoglobin. the type of β-thalassemia mutation affects on the β-globin chain synthesis that appears as β ° ، β + and β ++ -thalassemia. the presence of xmni polymorphic site at the 5 َ region of the g γ-globin gene affects on the rate of g γ chain synthesis and in some con...

background: approximately 180 mutations have been described in β-thalassemia worldwide with specific spectrum in each ethnic population. this study determines the spectrum and the frequency of β-thalassemia mutations in patients with β-thalassemia trait and sickle cell-β-thalassemia.   methods: fifteen compound heterozygous sickle cell thalassemia (sct) and 23 β-thalassemia trait patients were ...