نتایج جستجو برای: α and vegf p0001 swimming alone significantly decreased hif1

تعداد نتایج: 16889566  

Journal: :علوم زیستی ورزشی 0
احمد جعفری دانشجوی دکتری فیزیولوژی ورزشی دانشگاه مازندران، بابلسر، ایران شادمهر میردار دانشیار دانشگاه مازندران، بابلسر، ایران محسن زروار کارشناس ارشد تربیت بدنی دانشگاه تهران، تهران، ایران

the aim of this study was to examine the effect of swimming submaximal training and cadmium consumption on cardiac hif1-α and vascular endothelial growth factor (vegf) in pregnant rats. 32 pregnant wistar rats were randomly divided into 4 groups: cadmium, swimming, cadmium+swimming and control. experimental groups performed the swimming protocol for 3 weeks, 5 sessions a week for 60 minutes per...

Journal: :Tropical Journal of Pharmaceutical Research 2022

Purpose: To investigate the effect of S-adenosyl-L-methionine (SAM) on angiogenesis and fibrosis in heart rats with myocardial infarction (MI), to determine mechanism action.Methods: Sprague Dawley MI received SAM treatment (15 mg/kg) intraperitoneally. The cumulative survival (%) was recorded their rate survival. Hematoxylin-eosin staining, echocardiography, hemodynamics were also performed. I...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه بیرجند - دانشکده کشاورزی 1390

abstract this study is carried out to determine the chemical composition in the three vegetative stages of the haloxylon sp., degradation parameters, with adding naoh and ca(oh2 ). for this purpose, in may and october and january 2010 enough some haloxylon sp. of the ammary area was prepared. crude protein and ash percentage are decrease, neutral detergent fiber percentage with pragress stage ...

2015
Rossana Berardi Alessandro Brunelli Silvia Pagliaretta Vittorio Paolucci Alessandro Conti Gaia Goteri Majed Refai Cecilia Pompili Giulia Marcantognini Francesca Morgese Zelmira Ballatore Agnese Savini Mariagrazia De Lisa Miriam Caramanti Matteo Santoni Antonio Zizzi Francesco Piva Paola Mazzanti Azzurra Onofri Armando Sabbatini Marina Scarpelli Stefano Cascinu

We aimed to analyze genotypes of VEGF-A, VEGFR2, Flt4, PDGFRα, HIF-1α and ERCC1 and their correlation with thymic tumor risk and patient outcome. DNA of 57 consecutive patients (43 thymomas and 14 thymic carcinomas) who underwent total thymectomy at our Institution was extracted from paraffin-embedded tissue. We selected polymorphisms in the following genes:HIF1-α (rs2057482T > C, rs1951795A > ...

Journal: :Histology and histopathology 2013
Mariusz Adam Goscinski Jahn Marthin Nesland Karl-Erik Giercksky Hari Prasad Dhakal

OBJECTIVE Hypoxia inducible factor α (HIF1-α) is a key protein regulating the response of a variety of genes and pathways, including angiogenesis, to hypoxic stimuli. High vascularity in various carcinomas correlates with invasion and metastasis. Assessment of primary tumor vascularity and HIF1-α expression in esophageal carcinomas was an objective of this study. METHODS The vascularity in es...

2012
Marie Toussaint Laurence Fievez Christophe J Desmet Dimitri Pirottin Frédéric Farnir Fabrice Bureau Pierre Lekeux

BACKGROUND Recurrent airway obstruction (RAO, also known as equine heaves) is an inflammatory condition caused by exposure of susceptible horses to organic dusts in hay. The immunological processes responsible for the development and the persistence of airway inflammation are still largely unknown. Hypoxia-inducible factor (Hif) is mainly known as a major regulator of energy homeostasis and cel...

Journal: :American journal of cancer research 2017
Jianping Li Xin Meng Jing Hu Ying Zhang Yunzhi Dang Lichun Wei Mei Shi

Heparanase (HPSE1) is elevated in various types of cancers including cervical cancer, and correlated with poor prognosis. Current study is to investigate the effects of HPSE1 on radiation response in cervical cancer. Colony formation assays after radiation were performed to compare the radiation response among control, HPSE1 knockdown and HPSE1 overexpression HeLa cells. The mRNA and protein le...

Journal: :research in molecular medicine 0
safoura seifi babol university of medical sciences ghorban maliji babol university of medical sciences mina motallebnejad babol university of medical sciences ehsan maliji babol university of medical sciences mahmood khosravi samani babol university of medical sciences ramin farokhi babol university of medical sciences

background : recurrent aphthous stomatitis (ras) is one of the most common mucosal ulcerative of oral cavity. role of immune system, especially cytokines in immunopathogenesis of aphthous stomatitis was not highly considered. the aim of this study was to evaluate the levels of salivary cytokines, including vegf-r3, tgf-&beta1;, tnf-α, and il-17a/f in patients with ras in two clinical stages, ul...

2016
Anna P. Hnatiuk Sang‐Ging Ong Fernanda D. Olea Paola Locatelli Johannes Riegler Won Hee Lee Cheng Hao Jen Andrea De Lorenzi Carlos S. Giménez Rubén Laguens Joseph C. Wu Alberto Crottogini

BACKGROUND Bone marrow mesenchymal stromal cells (BMMSCs) are cardioprotective in acute myocardial infarction (AMI) because of release of paracrine angiogenic and prosurvival factors. Hypoxia-inducible factor 1-α (HIF1-α), rapidly degraded during normoxia, is stabilized during ischemia and upregulates various cardioprotective genes. We hypothesized that BMMSCs engineered to overexpress mutant, ...

2017
Dhananjay Pal

Introduction A continuous oxygen supply is pivotal for tissue development, regeneration, proper maintenance, and homeostasis of the body. During oxidative phosphorylation oxygen (O2) is necessary for the cells to produce ATP. This process produces higher energy than glycolysis. O2 is an essential element for cell survival, membrane transport, regulation of cell signaling, and gene expression. D...

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