نتایج جستجو برای: α and vegf (p=0.001). swimming alone significantly decreased hif1
تعداد نتایج: 16889566 فیلتر نتایج به سال:
the aim of this study was to examine the effect of swimming submaximal training and cadmium consumption on cardiac hif1-α and vascular endothelial growth factor (vegf) in pregnant rats. 32 pregnant wistar rats were randomly divided into 4 groups: cadmium, swimming, cadmium+swimming and control. experimental groups performed the swimming protocol for 3 weeks, 5 sessions a week for 60 minutes per...
Purpose: To investigate the effect of S-adenosyl-L-methionine (SAM) on angiogenesis and fibrosis in heart rats with myocardial infarction (MI), to determine mechanism action.Methods: Sprague Dawley MI received SAM treatment (15 mg/kg) intraperitoneally. The cumulative survival (%) was recorded their rate survival. Hematoxylin-eosin staining, echocardiography, hemodynamics were also performed. I...
بررسی ارزش غذایی تاغ و عمل آوری آن با سود و آهک در مراحل مختلف رشدبا استفاده از روش کیسه های نایلونی
abstract this study is carried out to determine the chemical composition in the three vegetative stages of the haloxylon sp., degradation parameters, with adding naoh and ca(oh2 ). for this purpose, in may and october and january 2010 enough some haloxylon sp. of the ammary area was prepared. crude protein and ash percentage are decrease, neutral detergent fiber percentage with pragress stage ...
We aimed to analyze genotypes of VEGF-A, VEGFR2, Flt4, PDGFRα, HIF-1α and ERCC1 and their correlation with thymic tumor risk and patient outcome. DNA of 57 consecutive patients (43 thymomas and 14 thymic carcinomas) who underwent total thymectomy at our Institution was extracted from paraffin-embedded tissue. We selected polymorphisms in the following genes:HIF1-α (rs2057482T > C, rs1951795A > ...
OBJECTIVE Hypoxia inducible factor α (HIF1-α) is a key protein regulating the response of a variety of genes and pathways, including angiogenesis, to hypoxic stimuli. High vascularity in various carcinomas correlates with invasion and metastasis. Assessment of primary tumor vascularity and HIF1-α expression in esophageal carcinomas was an objective of this study. METHODS The vascularity in es...
BACKGROUND Recurrent airway obstruction (RAO, also known as equine heaves) is an inflammatory condition caused by exposure of susceptible horses to organic dusts in hay. The immunological processes responsible for the development and the persistence of airway inflammation are still largely unknown. Hypoxia-inducible factor (Hif) is mainly known as a major regulator of energy homeostasis and cel...
Heparanase (HPSE1) is elevated in various types of cancers including cervical cancer, and correlated with poor prognosis. Current study is to investigate the effects of HPSE1 on radiation response in cervical cancer. Colony formation assays after radiation were performed to compare the radiation response among control, HPSE1 knockdown and HPSE1 overexpression HeLa cells. The mRNA and protein le...
background : recurrent aphthous stomatitis (ras) is one of the most common mucosal ulcerative of oral cavity. role of immune system, especially cytokines in immunopathogenesis of aphthous stomatitis was not highly considered. the aim of this study was to evaluate the levels of salivary cytokines, including vegf-r3, tgf-&beta1;, tnf-α, and il-17a/f in patients with ras in two clinical stages, ul...
BACKGROUND Bone marrow mesenchymal stromal cells (BMMSCs) are cardioprotective in acute myocardial infarction (AMI) because of release of paracrine angiogenic and prosurvival factors. Hypoxia-inducible factor 1-α (HIF1-α), rapidly degraded during normoxia, is stabilized during ischemia and upregulates various cardioprotective genes. We hypothesized that BMMSCs engineered to overexpress mutant, ...
Introduction A continuous oxygen supply is pivotal for tissue development, regeneration, proper maintenance, and homeostasis of the body. During oxidative phosphorylation oxygen (O2) is necessary for the cells to produce ATP. This process produces higher energy than glycolysis. O2 is an essential element for cell survival, membrane transport, regulation of cell signaling, and gene expression. D...
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