ôbjective: to investigate the pharmacokinetics (pk) and pk- pharmacodynamic (pd) relationship of methadone in a cohort of outpatients undergoing methadone maintenance treatment (mmt). methods: sixty male patients undergoing mmt with a mean ±sd methadone daily dosage of 58 ± 34 mg were enrolled in this study. â 5-ml blood sample was collected before the daily intake of methadone. âs a pd measure...

detoxification of children who are born from substance dependent mothers or those who are substance dependent themselves as a result of being abused by their families is a major concern. this report describes withdrawal symptoms and the way of abstinence in a 2.5 year-old girl who was dependent to opium. âfter that she was given opium for nearly two years suppress withdrawal symptoms, methadone...

For visualization of multivariable data, multivariate cube meets with the limitation of screen and human vision. Retinal variables are integrated into multivariate cube to enhance its visual characteristics. The selective feature of variables and associative feature of the values of the same variable are improved with the integration of retinal variable into the set of visual variables. The sel...

The GM-MDS conjecture of Dau et al. (ISIT 2014) speculates that the MDS condition, which guarantees the existence of MDS matrices with a prescribed set of zeros over large fields, is in fact sufficient for existence of such matrices over small fields. We prove this conjecture.

ôbjective: the purpose of the present preliminary study was to explore the prevalence of nonmedical abuse of benzodiazepines in a group of opiate-dependent patients who were on methadone maintenance treatment (mmt) program in outpatient clinics in the south-west of tehran, ïran. methods: 114 male and female opiate-dependent clients who met dsm.ïv-tr criteria for opiate dependence with mean age ...

A major deficiency in state-of-the-art automatic speech recognition (ASR) systems is the lack of robustness in additive and convolutional noise. The model of auditory perception (PEMO), developed by Dau et al. (1996a) for psychoacoustical purposes, partly overcomes these difficulties when used as a front end for automatic speech recognition. To further improve the performance of this auditory-b...

In this section, we briefly present the formalism we use. This formalism aims at describing the state of a system and its dynamic behaviour in an algebraic framework [DG 94]. It was first introduced in a case study on a formal specification of the embedded safety part of an automatic subway pilot [DM 91], [Dau 92], [DGM 93], in order to cope with the large number of variables whose values made ...

1 Formal Logic with Conceptual Graphs 3 Frithjof Dau 1.