ôbjective: to investigate the pharmacokinetics (pk) and pk- pharmacodynamic (pd) relationship of methadone in a cohort of outpatients undergoing methadone maintenance treatment (mmt). methods: sixty male patients undergoing mmt with a mean ±sd methadone daily dosage of 58 ± 34 mg were enrolled in this study. â 5-ml blood sample was collected before the daily intake of methadone. âs a pd measure...

ôbjective: the goal of this study was achieving a better understanding of the bowen family systems theory, especially regarding the relationships between differentiation of self, quality of relationship with parents and health dimensions in a sample of ïranian college students. methods: â convenient sample of 210 students (102 female and 108 male) participated in the present study. they were se...

ôbjective: the mood disorder questionnaire (mdq) has been designed as a screening self-report inventory for diagnosing bipolar mood disorders. this study investigated the validity and the optimal cut-off threshold of the persian version of mdq in a group of ïranian depressive patients. methods: ône hundred and twenty patients with probable diagnosis of mood disorders attending psychiatric clini...

there is increasing evidence of rapidly growing serious, pervasive, and expensive methamphetamine problem in ïran in recent years - a malicious social phenomenon with widespread psychological, familial and economic adversities - which contributes to theft, murder, suicide, violence, and divorce. substantial cases of acute psychiatric problems are increasingly seen following methamphetamine use ...

ôbjective: ço-morbidity of personality disorders with illicit drug abuse has a deleterious effect on the management outcome of both conditions. this study was conducted to assess the prevalence of different personality disorders among substance dependent patients in an ïranian city (ïsfahan) with a view to have a better understanding of various management strategies. methods: â total of 368 dif...

ôbjectives: the current study tested differences in depression, anxiety, and stress among ïranian wives with and without a history of spousal abuse. methods: the physically abused wives (n = 40) were among those who had been referred to a local forensic medical center. the control group (n = 40) comprised married women living in the same area of the city as the experimental group. the persian f...

ôbjective: üniversity students’ mental health affects not only their educational achievements, but also their professional future. the authors assessed the prevalence of suicidal ideation, depression, and aggression among students of three major universities in ïsfahan, ïran. methods: ïn 2008, 470 students were entered into the study using a convenience sampling method. the three measurement to...