ïn the last two decades, the importance of developing strategies that reduce the burden of new onset psychosis on affected persons, their families, and the community has been recognized. this article reviews the literature on first-episode psychosis (fëp) in ïran. ïn the last decade, several studies on fëp have been published in tehran concerning duration of untreated psychosis (düp), pathways ...

Background: Cognitive impairment is a common symptom in both Schizophrenia (SZ) and Bipolar Disorder (BD), and studies have demonstrated memory impairment in patients with these disorders. Objectives: To compare memory impairment in patients with SZ, BD with psychosis, and BD without psychosis. Materials & Methods: This study was a cross-sectional study conducted on 42 patients referred to Sh...

Abstract Background: Tramadol is a centrally acting opioid analgesic used to treat moderate to sever pain. It has more advantage and less opioid adverse effects than conventional opioid analgesia. Case Report: This article reports a patient with tramadol dependency that had psychosis after tramadol withdrawal. Conclusion: By the increase of tramadol usage for relief of chronic pain, t...

objective: this study was conducted to identify the characteristics of patients with psychosis who had escaped from hospital or were discharged prematurely and against medical advice. method: we carried out this retrospective study on 72 patients with psychosis who were discharged prematurely over a 38-month period and compared them to 76 patients with psychosis who were discharged according to...

although many studies have highlighted the role of gamma-aminobutyric acid (gaba) in the pathophysiology of psychosis, there is no drug-induced animal model in which gaba is manipulated. in this article we propose a hypothetical animal model for psychosis based on the silencing gabaergic system.  the presentation also suggest pre-pulse inhibition test as a preferred approach towards proving thi...

introduction: it has been known for a long time in the french-speaking, but not the english-speaking literature that travel can exacerbate pre-existing psychosis. the purpose of this article was to review the literature on this subject and present recommendations for prevention. methods: for this narrative review of the literature on travel risks in individuals with pre-existing psychosis, appr...

Brucellosis is an endemic zoonotic infectious disease in Middle East countries including Iran. This infection may involve central nervous system. Psychosis has been reported in rare cases with chronic brucellosis.A 26-year-old male shepherd patient who developed neuro-brucellosis and psychosis is presented. He had hallucinations (visual and auditory) and delusions. He was also impulsive and had...

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Psychotic disorders have been observed in association with some autoimmune disorders. Moreover, autoimmune mechanisms have been recently considered in evaluation of schizophrenia spectrum disease managements. Vitiligo is one of the autoimmune diseases, but there is no report of vitiligo association with psychosis. We report three patients with vitiligo and schizophrenia spectrum disease that ar...