It has been shown that inflammation reduces the effectiveness of sympathetic nerves in the regulation of knee joint blood flow, and the joint vascular- ß adrenoceptors are changed due to acute inflammation from a majority of ß-1 to an equality of ß-1 and ß-2 receptors.. To investigate the role of sympathetic nerves in nerve induced vasoconstriction and changes in joint vascular ß-adrenoceptors ...

Perioperative myocardial infarction is a leading cause of postoperative morbidity and mortality (1). The etiology of postoperative MI is the subject of some debate but is thought to include prolonged ischemia resulting from tachycardia (2). Perıoperatıve blockade could prevent perioperative cardiac damage and improve long-term cardiac outcome in noncardiac surgical patients. The beneficial effe...

The nomenclature of the Adrenoceptors has been agreed by NC-IUPHAR Subcommittee on [64, 194]. Adrenoceptors, α1 three α1-adrenoceptor subtypes α1A, α1B and α1D are activated endogenous agonists (-)-adrenaline (-)-noradrenaline. -(-)phenylephrine, methoxamine cirazoline prazosin doxazosin antagonists considered selective for α1- relative to α2-adrenoceptors. [3H]prazosin [125I]HEAT (BE2254) rela...

The effect of aqueous-ethanolic extract of Zataria multiflora Boiss (Labiatae), on βadrenoceptors was examined on tracheal chains of guinea pigs. The effects of three concentrations of aqueous-ethanolic extract (0.05, 0.1 and 0.2 mg/mL), 10 nM propranolol, and saline on β-adrenoceptors were tested (n=8). The results showed clear leftward shifts in isoprenaline curves obtained in the presence of...

This cross-sectional study aimed to assess perceptions of healthy food and motivation for health behaviour (MHB) in different Mediterranean countries. Multiple linear regression was used identify the association between perception MHB The highest observed Portugal (median 38.0; IQR 7.0) lowest Greece 34.0; 8.0). Compared Portuguese respondents, respondents from Croatia (ß=0.35; p < 0.001), Egyp...

the effect of epinephrine on phosphatidate phosphohydrolase (pap) activity of isolated human hepatocytes was studied. epineprine inhibited the enzyme activity progressively at concentrations above 0.1 µm, reaching a maximum inhibition of 64.5% at 100 µm concentration. inclusion of alprenolol, a β-receptor blocker, in the incubation mixture abolished the inhibitory effect of epinephrine on pap, ...

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Abstract Funding Acknowledgements Type of funding sources: None. onbehalf PREDICT-VT Heart failure (HF) still develops in 4% up to 28% STEMI pts treated by pPCI, with the highest incidence first year. Accurate and early identification high-risk patients would allow targeted personalized intensive treatment . Aim current study is a sub-study (NCT03263949). Its aim define multi-parametric model f...