نتایج جستجو برای: ?6 Integrin
تعداد نتایج: 978305 فیلتر نتایج به سال:
Purpose: To compare the effect of laminin and gelatin on short-term culture of spermatogonial stem cells (SSCs) from neonatal mouse testes.Materials and Methods: Cell suspension containing SSCs were isolated from testes of 6 day-old mice and cultured in the presence of Glial-derived neuroterophic factor (GDNF), Epidermal Growth Factor (EGF) and Basic Fibroblastic Growth Factor (bFGF) on laminin...
Introduction: Although the effect of adriamycin, a chemical drug used to treat cancer, is known to affect gametogenesis and ovarian function, the drug’s effect on endometrial receptivity and expression of integrin genes is unclear. To fill this gap, we aimed to investigate the effect of adriamycin on the expression of integrin genes that play a role in endometrial receptivity. Methods: A total...
Introduction: Skeletal muscle is a flexible and ever changing tissue and the role of costameric proteins in its response to different stimuli is not well defined. The aim of this study was to investigate the effect of progressive resistance exercise on β1 integrin and vinculin proteins in fast and slow twitch skeletal muscles of male rats. Methods: Twelve male Wistar rats (weight: 298±5.2 gr...
Integrins mediate cell-cell and cell-extracellular matrix interactions and play key roles in development. beta(6) integrin expression has been demonstrated in human fetal kidney at a higher level than in the adult, making beta(6) integrin a marker of interest for the study of development of the nephron. The aims of this study were to determine the cDNA sequence for the mouse beta(6) integrin an...
Background: The ovariectomized animals are good models to evaluate the effect of different steroid hormone treatments on implantation events and the pattern of integrin expression. Therefore, this study was performed to compare the expression of integrins and osteopontin (OPN) in correlation with pinopode development in ovariectomized mice endometrium which was subjected to steroid hormones. Me...
The distribution of 6/ 3 integrin in adhesion complexes at the basal membrane in human normal and cancer prostate glands was analyzed in 135 biopsies from 61 patients. The levels of the polarized 6/ 3 integrin expression at the basal membrane of prostate tumor glands were determined by quantitative immunohistochemistry. The 6/ 3 integrin expression was compared with Gleason sum score, pathologi...
The α(6)β(4) integrin promotes carcinoma invasion through its ability to promote directed migration and polarization of carcinoma cells. In this study, we explore how the α(6)β(4) integrin cooperates with lysophosphatidic acid (LPA) to activate Rho and Rac small GTPases. Through the use of dominant negative Rho constructs, C3 exotransferase, and Rho kinase inhibitor, we find that Rho is critica...
هدف از مطالعه حاضر ارزیابی اثر ماتریکس برونسلولی نانو رشتهای پلیآمید بر تکثیر و عملکرد سلولهای بنیادی اسپرماتوگونی (SSCs) بچه موش 6 رو در محیط In Vitro بوده است. سلولهای بنیادی اسپرماتوگونی، از بیضه موش 6 روزه جدا شده و در خانههای یک ظرف کشت 6 خانهای (3 خانه آن توسط ورقه نانوفیبر پوشانده بوده) به طور جداگانه در حضور فاکتورهای رشد GDNF bFGF و EGF با سه بار تکرار کشت داده شدند. تعداد کلنی...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید