نتایج جستجو برای: /cd16

تعداد نتایج: 2438  

Journal: :Infekciâ i Immunitet 2021

A search for new targeted therapeutic strategies based on examining immunopathogenetic mechanisms emerging co-infections is relevant and may further contribute not only to optimizing choice of immunotropic drugs, but also achieving positive clinical immunological remission abnormal infectious processes. Previously, our studies found that recurrent viral-bacterial respiratory infections are asso...

Mahbubeh Soofi Nader Tajik, Parisa Farnia Tahereh Mousavi,

Background: Protective immune responses induced in the majority of people infected with Mycobacterium tuberculosis enable them to control TB infection. Objective: The aim of this study was to investigate CD56 and CD16 positive peripheral blood mononu-clear cells (PBMCs) and leukocyte subsets from multi-drug resistant pulmonary tuber-culosis (MDR-TB), and compare them with nonresistant (NR) TB p...

2013
Giorgio Ghigliotti Chiara Barisione Silvano Garibaldi Claudio Brunelli Daniela Palmieri Giovanni Spinella Bianca Pane Paolo Spallarossa Paola Altieri Patrizia Fabbi Gianmario Sambuceti Domenico Palombo

Proinflammatory components are present in abdominal aortic aneurysm (AAA). Circulating monocytes display heterogeneity, and three subsets have been identified, based on the differential expression for CD14 and CD16 receptors: CD14(+)CD16(−), classical, CD14(+)CD16(+), intermediate and CD14(dim)CD16(+), non-classical monocytes. Increased proinflammatory CD16+ monocytes with high expression of CD...

Journal: :European heart journal 2011
Kyrill S Rogacev Sarah Seiler Adam M Zawada Birgit Reichart Esther Herath Daniel Roth Christof Ulrich Danilo Fliser Gunnar H Heine

AIMS Patients with chronic kidney disease (CKD) pose a worldwide growing burden to health care systems due to accelerated atherosclerosis and subsequent high cardiovascular (CV) morbidity. Atherogenesis is prominently driven by monocytes and monocyte-derived macrophages. The expression of CD14 and CD16 characterizes three monocyte subsets: CD14(++)CD16(-), CD14(++)CD16(+), and CD14((+))CD16(+) ...

Journal: :Journal of immunology 2016
Anne Waschbisch Sina Schröder Dana Schraudner Laura Sammet Babette Weksler Arthur Melms Sabine Pfeifenbring Christine Stadelmann Stefan Schwab Ralf A Linker

Monocytes represent a heterogeneous population of primary immune effector cells. At least three different subsets can be distinguished based on expression of the low-affinity FcγRIII: CD14(++)CD16 -: classical monocytes, CD14(++)CD16(+) intermediate monocytes, and CD14(+)CD16 ++: non-classical monocytes. Whereas CD16 -: classical monocytes are considered key players in multiple sclerosis (MS), ...

Journal: :Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2015
Kyrill S Rogacev Adam M Zawada Johanna Hundsdorfer Marina Achenbach Gerhard Held Danilo Fliser Gunnar H Heine

BACKGROUND Monocytes are critical in innate immunity and transplantation. Three monocyte subsets exist, CD14(++)CD16(-), CD14(++)CD16(+) and CD14(+)CD16(++) monocytes; cell counts of CD14(++)CD16(+) and CD14(+)CD16(++) monocytes are increased in pre-transplant chronic kidney disease. Interestingly, the effect of immunosuppressants on monocyte heterogeneity has not been well studied. METHODS T...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2013
Andres Wiernik Bree Foley Bin Zhang Michael R Verneris Erica Warlick Michelle K Gleason Julie A Ross Xianghua Luo Daniel J Weisdorf Bruce Walcheck Daniel A Vallera Jeffrey S Miller

PURPOSE The graft versus leukemia effect by natural killer (NK) cells prevents relapse following hematopoietic stem cell transplantation. We determined whether a novel bispecific killer cell engager (BiKE) signaling through CD16 and targeting CD33 could activate NK cells at high potency against acute myelogenous leukemia (AML) targets. EXPERIMENTAL DESIGN We investigated the ability of our fu...

Journal: :Arteriosclerosis, thrombosis, and vascular biology 2011
Christine Poitou Elise Dalmas Mariana Renovato Vanessa Benhamo Froogh Hajduch Meriem Abdennour Jean-François Kahn Nicolas Veyrie Salwa Rizkalla Wolf-Hervé Fridman Catherine Sautès-Fridman Karine Clément Isabelle Cremer

OBJECTIVE Studies suggest the implication of CD16(+) subpopulations (CD14(+)CD16(+), CD14(dim)CD16(+)) in inflammatory diseases. We aimed to determine the frequency of these subpopulations during weight loss in obesity and diabetes, conditions associated with changes in systemic inflammation, and we tested the link with subclinical atherosclerosis. METHODS AND RESULTS CD14(dim)CD16(+) and CD1...

Journal: :The Journal of Experimental Medicine 2003
Petronela Ancuta Ravi Rao Ashlee Moses Andrew Mehle Sunil K. Shaw F. William Luscinskas Dana Gabuzda

CD16+ monocytes represent 5-10% of peripheral blood monocytes in normal individuals and are dramatically expanded in several pathological conditions including sepsis, human immunodeficiency virus 1 infection, and cancer. CD16+ monocytes produce high levels of proinflammatory cytokines and may represent dendritic cell precursors in vivo. The mechanisms that mediate the recruitment of CD16+ monoc...

Journal: :Journal of immunology 2009
Natalya V Serbina Mathew Cherny Chao Shi Sharon A Bleau Nancy H Collins James W Young Eric G Pamer

Aspergillus fumigatus is an environmental fungus that causes life-threatening infections in neutropenic patients. In the absence of intact innate immunity, inhaled A. fumigatus spores (conidia) germinate in the lung, forming hyphae that invade blood vessels and disseminate to other tissues. Although macrophages and neutrophils are postulated to provide defense against invasive fungal infection,...

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