the aim of the present paper is to define and study (ic)$lm$-fuzzytopological spaces, a generalization of (weakly) induced $lm$-fuzzytopological spaces. we discuss the basic properties of(ic)$lm$-fuzzy topological spaces, and introduce the notions ofinterior (ic)-fication and exterior (ic)-fication of $lm$-fuzzytopologies and prove that {bf iclm-ftop} (the category of(ic)$lm$-fuzzy topological ...

The aim of the present paper is to define and study (IC)$LM$-fuzzytopological spaces, a generalization of (weakly) induced $LM$-fuzzytopological spaces. We discuss the basic properties of(IC)$LM$-fuzzy topological spaces, and introduce the notions ofinterior (IC)-fication and exterior (IC)-fication of $LM$-fuzzytopologies and prove that {bf ICLM-FTop} (the category of(IC)$LM$-fuzzy topological ...

The metabolism of 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-N-phenethyl-acetamide (indomethacin phenethylamide, LM-4108), a highly selective cyclooxygenase-2 inhibitor, was studied in rat, mouse, and human liver microsomes. The primary site of oxidation in all species examined was on the methylene carbons of the phenethyl side chain to form the 1'- and 2'-hydroxy and 2'-oxo metab...

Electron paramagnet ic resonance, magnet ic suscepti bility and superox ide d ismutase (SOD) activity measurements o f imidazolate bri dged [(Salval)Cu-lm-Cu(Salval)]Na, [(Salval)Cu-lm-Ni (Salval)]Na and [(Salval)Cu-lm-Zn(Sa lva l)1 a complexes, [where salval = salicyledenevalinate, im = imidazolate ion,] are described . Related mononuclear copper(l l) compel xes are also synt hesized . T he p ...

The prognosis of leptomeningeal metastasis (LM) from solid tumors is extremely poor, especially for patients with adverse prognostic factors. In this phase II clinical trial, we evaluated the efficacy and safety of intrathecal chemotherapy (IC) combined with concomitant involved-field radiotherapy (IF-RT) for treating LM from solid tumors with adverse prognostic factors. Fifty-nine patients wit...

The combination therapy of the Artemisinin-derivative Artemether (ART) with Lumefantrine (LM) (Coartem®) is an important malaria treatment regimen in many endemic countries. Resistance to Artemisinin has already been reported, and it is feared that LM resistance (LMR) could also evolve quickly. Therefore molecular markers which can be used to track Coartem® efficacy are urgently needed. Often, ...

AIM To study the role of mRNA secondary structure stability in antisense drug design and obtain better antisense candidates against neu/HER-2/erbB-2 mRNA than previous report. METHODS Program RNAstructure was utilized to simulate the secondary structures of HER-2 mRNA. Then 21 antisense phosphorothioate oligodeoxynucleotides (S-ODN) targeting different parts of secondary structural motif were...

In images of textured surfaces, orientation flows formed by perspective convergence invariably convey 3D shape. We show that orientation flows formed by contrast-modulated (CM) and illusory contours (IC) convey 3D shape, and that both stimulus types induce 3D shape aftereffects on CM and IC test stimuli. Adaptation to luminance-modulated (LM) orientation flows induce robust 3D shape aftereffect...

BACKGROUND AND STUDY AIMS l-Menthol (LM), sprayed on the distal gastric mucosa, is a safe antispasmodic agent used during esophagogastroduodenoscopy (EGD). However, it seems to affect gastric mucosal endoscopic findings. Therefore, we evaluated whether LM causes specific changes and impacts the endoscopic morphology of gastric lesions. PATIENTS AND METHODS A total of 98 patients scheduled to ...

We have designed and fabricated two-color infrared light emitting diode (LED) emitting in the wavelength regions of 3–4 lm and 5–10 lm. The interband cascade (IC) LED device was grown on n-type GaSb substrate and has 30 cascaded stages for the long-wave infrared (LWIR) and 15 cascaded stages for the mid-wave infrared (MWIR) emission bands. The two active regions are separated by a 0.5 lm thick ...