The phospholipid complex of the obtained aqueous fraction (AF) was prepared with Phospholipon 90H. The size of nanophytosomes was determined by dynamic light scattering. HPTLC fingerprinting of the AF was also performed. PTZ and ICES models were used to evaluate the anticonvulsant activity while Rotarod test, Elevated Plus maze test, and Forced swimming test were used to evaluate other neuropha...

Given their medical importance, natural products represent a tremendous source of drug discovery. The aim of this study was to investigate Malva sylvestris L. extract and fractions and their pharmacological activities followed by chemical identification. The aqueous fraction (AF) was identified as the bioactive fraction in the in vitro and in vivo assays. The AF controlled the neutrophil migrat...

OBJECTIVE To explore the influence of charred Gossamer urocteae (CGU) on the functions of primary cultured mouse oral fibroblasts and reveal its mechanism in wound healing. METHODS CGU was extracted with different solvents and ethanol extract (EE), ethyl acetate fraction (EF), n-butanol fraction (BF) and aqueous fraction (AF) were obtained. The effects of different fractions on the proliferat...

To ascertain whether an aqueous fraction of Perilla frutescens Britton (PfB/af) has advantageous anti-atopic dermatitis activity, we used a 2,4-dinitrofluorobenzene (DNFB)-induced animal model of atopic dermatitis symptoms to investigate the effects of the extract. We performed an ear swelling assay by comparing thickness of the DNFB-induced ear, and measured the numbers of eosinophils as well ...

renal dysfunction is a risk marker in patients who candidate for coronary artery bypass graft (cabg). renal disorder is associated with prolonged stays in intensive care unit and hospital, morbidity and mortality. aim of this study is specific evaluation of association between preoperative creatinine (cr) with atrial fibrillation (af) after elective off-pump cabg in non-diabetic male patients w...

Acetic acid-soluble and insoluble proteins were isolated from doughs mixed in the presence of N-ethylmaleimide (NEMI). Reducedpyridylethylated acetic acid-insoluble protein (AF) and reducedpyridylethylated acetic acid-soluble protein (BF) were sequentially fractionated into an acetic acid-insoluble fraction (F-0), an acidic 70% ethanol-insoluble fraction (F-I), a neutral 70% ethanol-insoluble f...

BACKGROUND Atrial fibrillation (AF) is the most common complication of cardiac surgery. Although it is managed easily, it can cause critical hemodynamic instabilities for intensive care patients. This observational study investigated the predictive power of P-wave dispersion (PWD) for the incidence of post cardiac surgery AF. METHODS Among patients undergoing isolated coronary artery bypass g...

BACKGROUND Antacids, anticholinergic drugs, histamine H2- receptor antagonists and irreversible proton pump inhibitors have been used for the treatment of gastric ulcers. However, prolonged use of these drugs may lead to series of adverse effects such as diarrhea, headache, rash, hypertension, muscular and joint pain. Therefore, there is an urgent need of more effective and safer treatments wit...

objective: the use of drugs with herbal origin is increasing for treatment of gastrointestinal (gi) disorders. rosa damascena (r. damascena) is a well-known plant suggested to have beneficial effect on gi system. in this study, the effect of aqueous fraction of r. damascena on the contractionsofisolated guinea pig ileum was investigated. materials and methods: aqueous fraction of plant was obta...