The Punica granatum L. var. granatum (pomegranate) has been demonstrated to exert antitumor effects on various types of cancer cells. The present study aimed to evaluate the medicinal herbs Punica granatum L. var. spinosa (apple punice) that are native to Iran. This study was determined to test the possible cytotoxic activity and induction of apoptosis on human prostate cell lines. The effect o...

PURPOSE Punica granatum L. var. granatum (Pomegranate), an herbaceous plant found in Iran, The aim of this study was to investigate the cytotoxic effects, induction of apoptosis, and the mechanism of cell death of ethanol extract from Punica granatum L. var. spinosa on the mouse fibrosarcoma cell line, WEHI-164. METHODS Various parts of the herbs were extracted from fruit using ethanol as the...

BACKGROUND Herbal drugs are considered alternative agents and have been used for several years around the world. Recurrent aphthous stomatitis (RAS) is one of the most common problems recognized by dentists and skin specialists. This problem is characterized by recurring, painful, small oral mucosal ulcers with a round or oval aspect that mostly appear in keratinized mucosa, cheeks, and on the ...

Pomegranate (Punica granatum) is an ancient fruit used in various systems of medicine for a variety of ailments. The study has been designed to investigate the role of ethanolic extract of rinds of Punica granatum as antimicrobial on 6 types of bacteria includes; Pseudomonas aeruginosa, Salmonella typhi, Staph aureus, E.coli, Streptococcus spp. and Klebsiella pneumonia and antifungal activity o...

In the present study the leaves of Punica granatum were subjected to phytochemical screening and the impact of the leaf extract of Punica granatum was tested against Bacillus subtilis, Staphylococcus aureus and Salmonella typhi. The phytochemical analysis revealed the presence of various phytochemicals such as alkaloids, tannins, phenols, flavonoid and saponins. Agar disk diffusion method was e...

Pomegranate (Punica granatum L.) has been cultivated from ancient times for its economic, ornamental and medicinal properties globally. Here, we report the isolation and characterization of 12 polymorphic microsatellite markers from a repeat-enriched genomic library of Punica granatum L. The genetic diversity of these loci was assessed in 60 genotypes of Punica granatum L. All loci were variabl...

This study aims to evaluate whether the Punica granatum fruit extract modulates the Angiotensin-II Type I receptor (AT1-R) and thromboxane B2 level in endothelial cells induced by plasma from preeclamptic patients. Endothelial cells were obtained from human umbilical vascular endothelial cells. At confluence, endothelial cells were divided into five groups, which included endothelial cells expo...

The chemical composition and minerals analysis of four different plant species viz., Hippophae rhamnoides, Azadirachta indica, Punica granatum and Ocimum sanctum leaves were studied. In the nutritional analysis the Punica granatum was found enriched source of ectin, crude fiber, sugar and vitamin C as compare with other targeted plant leaves. The fat contents was also found in valuable quantity...

INTRODUCTION Punica granatum is apotent source of polyphenolic compounds with strong free radicals scavenging activity. The skin lightening effects of Punica granatum are assumed due to ellagic acid which acts by chelating copper at the active site of tyrosinase. AIM To explore a topical microemulsion (O/W) of pomegranate (Punica granatum) extract for its control on skin erythema and melanin....