the solubility enhancement of poorly soluble compounds is an important task in pharmaceutical technology as it leads to better bioavailability and a more efficient application. fused dispersions (fds) of simvastatin (sim) using peo-ppo block copolymer were prepared which paved the way for the formation of an amorphous product with enhanced dissolution and bioavailability. the accumulative solub...

The aim of this study is to evaluate and compare the oral bioavailability nanonized progesterone (nano-PG) micronized (micro-PG) sustained release tablet formulation in healthy pregnant rabbits. High pressure compressed gas technology reduces particle size from 1.72 ± 2.5 μm 800 35 nm (nano-PG). DSC XRD showed that both micro-PG nano-PG were crystalline exist as form I. Higher melting enthalpy ...

Abstract: (Y2O3) and ethyl acetate as a mineralizer by hydrothermal method at a low temperature (T=.230°C, andP=100bars).The as-prepared powders were characterized by X-ray Diffraction (XRD), Fourier Transform InfraredSpectroscopy (FTIR), Scanning Electron Microscopy (SEM), UV-V Spectroscopy and Chemical Oxygen Demand(COD) of the sewage water, respectively. The results show that hydrothermal me...

WO3 and NiO-WO3 thin films of various thicknesses were deposited on an Al2O3-Si (alumina-silicon) substrate using high vacuum thermal evaporation. After annealing at 500C for 30 minutes in air, the crystallanity and surface morphology of WO3 and NiO-WO3 thin films were investigated using X-ray diffraction (XRD) and Scanning Electron Microscopy (SEM). It is observed that the WO3 thin films were ...

The objective of the present investigation was to enhance the oral bioavailability of practically insoluble Candesartan cilexetil [CC] by preparing nanosuspension. The nanosuspension was prepared by media milling using zirconium oxide beads and converted to solid state by spray drying. The spray dried nanosuspension of CC [SDCN] was evaluated for particle size, zeta potential, saturation solubi...