Leach, R. M., D. W. Sheehan, V. P. Chacko, and J. T. Sylvester. Energy state, pH, and vasomotor tone during hypoxia in precontracted pulmonary and femoral arteries. Am. J. Physiol. Lung Cell. Mol. Physiol. 278: L294–L304, 2000.—To assess effects of smooth muscle energy state and intracellular pH (pHi) on pulmonary arterial tone during hypoxia, we measured ATP, phosphocreatine, Pi, and pHi by 31...

Huang and Zhang cite{Huang} have introduced the concept of cone metric space where the set of real numbers is replaced by an ordered Banach space. Shojaei cite{shojaei} has obtained points of coincidence and common fixed points for s-Contraction mappings which satisfy generalized contractive type conditions in a complete cone metric space.In this paper, the notion of complete cone metric ...

This study investigates the role of extracellular signal-regulated kinases (ERKs) in angiotensin II (Ang II)-generated intracellular second messengers (cytosolic free Ca2+ concentration, ie, [Ca2+]i, and pHi) and in contraction in isolated vascular smooth muscle cells (VSMCs) from spontaneously hypertensive rats (SHR) and control Wistar Kyoto rats (WKY) using the selective mitogen-activated pro...

Integrin-linked kinase (ILK) has been implicated in Ca(2+)- independent contraction of smooth muscle via its ability to phosphorylate myosin. We investigated the possibility that this kinase might also phosphorylate and regulate the myosin light-chain phosphatase inhibitor proteins CPI-17 [protein kinase C (PKC)-dependent phosphatase inhibitor of 17 kDa] and PHI-1 (phosphatase holoenzyme inhibi...

We use numerical relativity simulations to explore the conditions for a canonical scalar field $\phi$ minimally coupled Einstein gravity generate an extended phase of slow contraction that robustly smooths universe wide range initial and then sets graceful exit stage. show achieve robustness it suffices potential $V(\phi)$ is negative $M_{\rm Pl}|V_{,\phi}/V|\gtrsim5$ during smoothing phase. al...

Serotonin (5-HT) and other contractile agonists stimulate Na(+)-H+ exchange in vascular smooth muscle. Since intracellular alkalinization, per se, stimulates contraction, we tested whether 5-HT-induced contraction was associated with an increased pHi. In HCO3(-)-free buffer (pHo 7.4), 5-HT (10(-5) M) increased pHi, as measured by 2',7'-bis(2-carboxyethyl)-5(6)-carboxyfluorescein fluorescence, f...

In this paper, we define \(\theta\)-\(\phi\)-contraction on a \(b\)-metric space into itself by extending \(\theta\)-\(\phi \)-contraction introduced Zheng {et al.} [D. W. Zheng, Z. Y. Cai, P. Wang, J. Nonlinear Sci. Appl., \(\bf 10\) (2017), 2662--2670] in metric and also, prove \(\theta \)-type theorem the setting of spaces as well framework \(b\)-rectangular spaces. Moreover, give some appli...

Inflammatory mediators released by macrophages (M phi) are believed to be involved in septic vasoplegia. To investigate the effect of M phi on vascular reactivity, excised rabbit carotids were exposed intraluminally either to peritoneal rabbit M phi, activated by 18 h of incubation with 1 microgram/ml lipopolysaccharide, or to the supernatants (SPN) derived from them. The contractile responses ...